(1Z)-1-methyl-3-oxo-2-phenyl-3-{[2-(2-thienyl)ethyl]amino}-1-propen-1-yl trifluoromethanesulfone

Base Information

Chemical Name:(1Z)-1-methyl-3-oxo-2-phenyl-3-{[2-(2-thienyl)ethyl]amino}-1-propen-1-yl trifluoromethanesulfone
CAS No.:938180-24-6
Molecular Formula:C₁₇H₁₆F₃NO₄S₂
Molecular Weight:419.446
Hs Code.:

Synonyms:(1Z)-1-methyl-3-oxo-2-phenyl-3-{[2-(2-thienyl)ethyl]amino}-1-propen-1-yl trifluoromethanesulfone

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Chemical Property of (1Z)-1-methyl-3-oxo-2-phenyl-3-{[2-(2-thienyl)ethyl]amino}-1-propen-1-yl trifluoromethanesulfone

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Technology Process of (1Z)-1-methyl-3-oxo-2-phenyl-3-{[2-(2-thienyl)ethyl]amino}-1-propen-1-yl trifluoromethanesulfone

There total 1 articles about (1Z)-1-methyl-3-oxo-2-phenyl-3-{[2-(2-thienyl)ethyl]amino}-1-propen-1-yl trifluoromethanesulfone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 938180-22-4
3-oxo-2-phenyl-N-[2-(2-thienyl)ethyl]butanamide

: 358-23-6
trifluoromethylsulfonic anhydride

: 938180-24-6
(1Z)-1-methyl-3-oxo-2-phenyl-3-{[2-(2-thienyl)ethyl]amino}-1-propen-1-yl trifluoromethanesulfone

Guidance literature:: With triethylamine; In dichloromethane; at -78 - 0 ℃;

Reference yield: 62.0%

: 874830-59-8
3-fluoro-2-methoxy-benzamide

: 938180-24-6
(1Z)-1-methyl-3-oxo-2-phenyl-3-{[2-(2-thienyl)ethyl]amino}-1-propen-1-yl trifluoromethanesulfone

: 938180-25-7
3-fluoro-N-((1Z)-1-methyl-3-oxo-2-phenyl-3-{[2-(2-thienyl)ethyl]amino}-1-propen-1-yl)-2-(methyloxy)benzamide

Guidance literature:: With caesium carbonate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; In 1,4-dioxane; for 16h; Heating / reflux;