N₂-[(2S)-2-hydroxy-4-methylpentanoyl]-N₁-[(6R,7R)-5-oxo-7-phenyl-1,4-thiazepan-6-yl]-L-phenylalaninamide

Base Information

• Chemical Name: N₂-[(2S)-2-hydroxy-4-methylpentanoyl]-N₁-[(6R,7R)-5-oxo-7-phenyl-1,4-thiazepan-6-yl]-L-phenylalaninamide
• CAS No.: 680229-41-8
• Molecular Formula: C₂₆H₃₃N₃O₄S
• Molecular Weight: 483.632

Synonyms:N₂-[(2S)-2-hydroxy-4-methylpentanoyl]-N₁-[(6R,7R)-5-oxo-7-phenyl-1,4-thiazepan-6-yl]-L-phenylalaninamide

Chemical Property of N₂-[(2S)-2-hydroxy-4-methylpentanoyl]-N₁-[(6R,7R)-5-oxo-7-phenyl-1,4-thiazepan-6-yl]-L-phenylalaninamide

Chemical Property:

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Technology Process of N₂-[(2S)-2-hydroxy-4-methylpentanoyl]-N₁-[(6R,7R)-5-oxo-7-phenyl-1,4-thiazepan-6-yl]-L-phenylalaninamide

There total 1 articles about N₂-[(2S)-2-hydroxy-4-methylpentanoyl]-N₁-[(6R,7R)-5-oxo-7-phenyl-1,4-thiazepan-6-yl]-L-phenylalaninamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-[(6,7-cis)-5-oxo-7-phenyl-1,4-thiazepan-6-yl]-L-phenylalaninamide (680231-22-5) + (S)-2-hydroxyl-3,3-dimethylbutyric acid (13748-90-8,498-36-2) → N2-[(2S)-2-hydroxy-4-methylpentanoyl]-N1-[(6R,7R)-5-oxo-7-phenyl-1,4-thiazepan-6-yl]-L-phenylalaninamide (680229-41-8) + C26H33N3O4S

Guidance literature:

With 4-methyl-morpholine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20 ℃;

upstream raw materials:

N-[(6,7-cis)-5-oxo-7-phenyl-1,4-thiazepan-6-yl]-L-phenylalaninamide

(S)-2-hydroxyl-3,3-dimethylbutyric acid

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