N²-benzoyl-9-(4'-methoxyphenyl)-2-oxo-2,9-dihydro-1H-purine-6-carboxamidine

Base Information

• Chemical Name: N²-benzoyl-9-(4'-methoxyphenyl)-2-oxo-2,9-dihydro-1H-purine-6-carboxamidine
• CAS No.: 943439-80-3
• Molecular Formula: C₂₀H₁₆N₆O₃
• Molecular Weight: 388.385
• Mol file: 943439-80-3.mol

Synonyms:N²-benzoyl-9-(4'-methoxyphenyl)-2-oxo-2,9-dihydro-1H-purine-6-carboxamidine

Chemical Property of N²-benzoyl-9-(4'-methoxyphenyl)-2-oxo-2,9-dihydro-1H-purine-6-carboxamidine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N²-benzoyl-9-(4'-methoxyphenyl)-2-oxo-2,9-dihydro-1H-purine-6-carboxamidine

There total 2 articles about N²-benzoyl-9-(4'-methoxyphenyl)-2-oxo-2,9-dihydro-1H-purine-6-carboxamidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

5-amino-4-[(N-benzoylcarbamoyl)cyanoformimidoyl]-1-(4-methoxyphenyl)-1H-imidazole → N2-benzoyl-9-(4'-methoxyphenyl)-2-oxo-2,9-dihydro-1H-purine-6-carboxamidine (943439-80-3)

Guidance literature:

In ethanol; at 20 ℃; for 144h;

DOI:10.1002/ejoc.200601025

Reference yield:

5-amino-1-(4'-methoxyphenyl)-4-(cyanoformimidoyl)imidazole (155579-28-5) → N2-benzoyl-9-(4'-methoxyphenyl)-2-oxo-2,9-dihydro-1H-purine-6-carboxamidine (943439-80-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 91 percent / acetonitrile / 3 h / -15 °C

2: 94 percent / ethanol / 144 h / 20 °C

In ethanol; acetonitrile;

DOI:10.1002/ejoc.200601025

Reference yield: 98.0%

N2-benzoyl-9-(4'-methoxyphenyl)-2-oxo-2,9-dihydro-1H-purine-6-carboxamidine (943439-80-3) → 9-(4'-methoxyphenyl)-2-oxo-2,9-dihydro-1H-purine-6-carboxamidrazone

Guidance literature:

With hydrazine hydrate; In ethanol; at 20 ℃; for 48h;

DOI:10.1002/ejoc.200601025

upstream raw materials:

5-amino-1-(4'-methoxyphenyl)-4-(cyanoformimidoyl)imidazole