4-fluorobenzene

Base Information

• Chemical Name: 4-fluorobenzene
• CAS No.: 29848-52-0
• Molecular Formula: C₁₀H₄F₇IO₄
• Molecular Weight: 448.033
• Mol file: 29848-52-0.mol

Synonyms:4-fluorobenzene

Chemical Property of 4-fluorobenzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-fluorobenzene

There total 5 articles about 4-fluorobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

4-fluoro-1-iodosylbenzene (120866-17-3) + trifluoroacetic anhydride (407-25-0) → 4-fluorobenzene (29848-52-0)

Guidance literature:

In dichloromethane; at -20 ℃;

Reference yield: 90.0%

4-fluoro-1-iodobenzene (352-34-1) + trifluoroacetyl peroxide (359-48-8) → 4-fluorobenzene (29848-52-0)

Guidance literature:

In dichloromethane; at -40 - 20 ℃; for 8h;

DOI:10.1055/s-2006-942543

Reference yield: 80.0%

4-fluoro-1-iodobenzene (352-34-1) + trifluoroacetic acid (76-05-1) → 4-fluorobenzene (29848-52-0)

Guidance literature:

With Oxone; In chloroform; at 20 ℃; for 1h;

DOI:10.1021/jo902733f

upstream raw materials:

4-fluoro-1-iodosylbenzene

trifluoroacetic anhydride

4-fluoro-1-iodobenzene

trifluoroacetic acid

Downstream raw materials:

(4-fluorophenyl)(hydroxy)-λ3-iodaneyl 4-methylbenzenesulfonate

1,4-dichloro-2-trifluoromethylbenzene