methyl N-{1-{[(tert-butoxycarbonyl)(4-fluorobenzyl)amino]methyl}-3-[methoxy(methyl)amino]propyl}glycinate

Base Information

Chemical Name:methyl N-{1-{[(tert-butoxycarbonyl)(4-fluorobenzyl)amino]methyl}-3-[methoxy(methyl)amino]propyl}glycinate
CAS No.:851726-60-8
Molecular Formula:C₂₁H₃₄FN₃O₅
Molecular Weight:427.516
Hs Code.:

Synonyms:methyl N-{1-{[(tert-butoxycarbonyl)(4-fluorobenzyl)amino]methyl}-3-[methoxy(methyl)amino]propyl}glycinate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of methyl N-{1-{[(tert-butoxycarbonyl)(4-fluorobenzyl)amino]methyl}-3-[methoxy(methyl)amino]propyl}glycinate

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Technology Process of methyl N-{1-{[(tert-butoxycarbonyl)(4-fluorobenzyl)amino]methyl}-3-[methoxy(methyl)amino]propyl}glycinate

There total 1 articles about methyl N-{1-{[(tert-butoxycarbonyl)(4-fluorobenzyl)amino]methyl}-3-[methoxy(methyl)amino]propyl}glycinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 851726-59-5
tert-butyl 4-fluorobenzyl{4-[methoxy(methyl)amino]-2-oxobutyl}-carbamate

: 616-34-2
methoxycarbonylmethylamine

: 851726-60-8
methyl N-{1-{[(tert-butoxycarbonyl)(4-fluorobenzyl)amino]methyl}-3-[methoxy(methyl)amino]propyl}glycinate

Guidance literature:: With sodium tris(acetoxy)borohydride; acetic acid; triethylamine; In tetrahydrofuran; at 20 ℃; for 42h;

Reference yield:

: 851726-60-8
methyl N-{1-{[(tert-butoxycarbonyl)(4-fluorobenzyl)amino]methyl}-3-[methoxy(methyl)amino]propyl}glycinate

: 851726-61-9
1-(4-fluorobenzyl)-5-{2-[methoxy(methyl)amino]ethyl}piperazine-2-one

Guidance literature:: methyl N-{1-{[(tert-butoxycarbonyl)(4-fluorobenzyl)amino]methyl}-3-[methoxy(methyl)amino]propyl}glycinate; With trifluoroacetic acid; In dichloromethane; at 0 - 20 ℃; for 2h;

With potassium carbonate; In water; at 100 ℃; for 0.5h;