(R)-2-mercapto-3-phenylacetic acid (R-thiomandelic acid)

Base Information

Chemical Name:(R)-2-mercapto-3-phenylacetic acid (R-thiomandelic acid)
CAS No.:16201-51-7
Molecular Formula:C₈H₈O₂S
Molecular Weight:168.216
Hs Code.:

Synonyms:(R)-2-mercapto-3-phenylacetic acid (R-thiomandelic acid)

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (R)-2-mercapto-3-phenylacetic acid (R-thiomandelic acid)

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Technology Process of (R)-2-mercapto-3-phenylacetic acid (R-thiomandelic acid)

There total 27 articles about (R)-2-mercapto-3-phenylacetic acid (R-thiomandelic acid) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 16201-52-8,103499-60-1,132958-61-3,14337-72-5
2-mercapto-2-phenylacetic acid methyl ester

: 4695-09-4,16201-50-6,16201-51-7,103616-08-6
α-mercaptophenylacetic acid

Guidance literature:: With sulfuric acid; water; at 0 ℃;
DOI:10.1016/j.bmcl.2018.01.059

Reference yield: 90.0%

: 41128-19-2
S-acetyl-α-phenyl-α-mercaptoacetic acid

: 4695-09-4,16201-50-6,16201-51-7,103616-08-6
α-mercaptophenylacetic acid

Guidance literature:: With ammonia; In methanol; at 0 - 20 ℃;

Reference yield: 75.0%

: 103499-53-2
(S)-methyl 2-acetylsulfanyl-2-phenylacetate

: 16201-51-7
(R)-2-mercapto-3-phenylacetic acid (R-thiomandelic acid)

: 103616-08-6
(S)-2-mercapto-2-phenylacetic acid

Guidance literature:: With hydrogenchloride; In N,N-dimethyl-formamide; for 96h; Title compound not separated from byproducts; Ambient temperature;
DOI:10.1021/jo00369a020