4-((S)-6-Benzyloxycarbonylamino-2-{[4-(benzyloxycarbonylamino-methyl)-cyclohexanecarbonyl]-amino}-hexanoylamino)-benzoic acid isopropyl ester

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Chemical Name:4-((S)-6-Benzyloxycarbonylamino-2-{[4-(benzyloxycarbonylamino-methyl)-cyclohexanecarbonyl]-amino}-hexanoylamino)-benzoic acid isopropyl ester
CAS No.:140135-19-9
Molecular Formula:C₄₀H₅₀N₄O₈
Molecular Weight:714.859
Hs Code.:

4-((S)-6-Benzyloxycarbonylamino-2-{[4-(benzyloxycarbonylamino-methyl)-cyclohexanecarbonyl]-amino}-hexanoylamino)-benzoic acid isopropyl ester

Synonyms:4-((S)-6-Benzyloxycarbonylamino-2-{[4-(benzyloxycarbonylamino-methyl)-cyclohexanecarbonyl]-amino}-hexanoylamino)-benzoic acid isopropyl ester

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Chemical Property of 4-((S)-6-Benzyloxycarbonylamino-2-{[4-(benzyloxycarbonylamino-methyl)-cyclohexanecarbonyl]-amino}-hexanoylamino)-benzoic acid isopropyl ester

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Technology Process of 4-((S)-6-Benzyloxycarbonylamino-2-{[4-(benzyloxycarbonylamino-methyl)-cyclohexanecarbonyl]-amino}-hexanoylamino)-benzoic acid isopropyl ester

There total 6 articles about 4-((S)-6-Benzyloxycarbonylamino-2-{[4-(benzyloxycarbonylamino-methyl)-cyclohexanecarbonyl]-amino}-hexanoylamino)-benzoic acid isopropyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2389-45-9
Boc-Lys(Z)-OH

: 140135-19-9
4-((S)-6-Benzyloxycarbonylamino-2-{[4-(benzyloxycarbonylamino-methyl)-cyclohexanecarbonyl]-amino}-hexanoylamino)-benzoic acid isopropyl ester

Guidance literature:: Multi-step reaction with 4 steps

2: tetrahydrofuran; dimethylformamide / Ambient temperature

3: 5.6 N HCl/dioxane

4: Et₃N / CHCl₃; dimethylformamide / Ambient temperature

With hydrogenchloride; triethylamine; In tetrahydrofuran; chloroform; N,N-dimethyl-formamide;
DOI:10.1248/cpb.39.2930

Reference yield:

: 18144-43-9
isopropyl 4-aminobenzoate

: 140135-19-9
4-((S)-6-Benzyloxycarbonylamino-2-{[4-(benzyloxycarbonylamino-methyl)-cyclohexanecarbonyl]-amino}-hexanoylamino)-benzoic acid isopropyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: tetrahydrofuran; dimethylformamide / Ambient temperature

2: 5.6 N HCl/dioxane

3: Et₃N / CHCl₃; dimethylformamide / Ambient temperature

With hydrogenchloride; triethylamine; In tetrahydrofuran; chloroform; N,N-dimethyl-formamide;
DOI:10.1248/cpb.39.2930

Reference yield:

: 27687-12-3
(1r,4r)-4-({[(benzyloxy)carbonyl]amino}methyl)cyclohexane-1-carboxylic acid

: 140135-19-9
4-((S)-6-Benzyloxycarbonylamino-2-{[4-(benzyloxycarbonylamino-methyl)-cyclohexanecarbonyl]-amino}-hexanoylamino)-benzoic acid isopropyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: SOCl₂

2: Et₃N / CHCl₃; dimethylformamide / Ambient temperature

With thionyl chloride; triethylamine; In chloroform; N,N-dimethyl-formamide;
DOI:10.1248/cpb.39.2930