rac-N-<2-benzyloxy-β-(4-benzyloxyphenyl)-3-methoxyphenethyl>-N-methylformamide

Base Information

Chemical Name:rac-N-<2-benzyloxy-β-(4-benzyloxyphenyl)-3-methoxyphenethyl>-N-methylformamide
CAS No.:97456-08-1
Molecular Formula:C₃₁H₃₁NO₄
Molecular Weight:481.591
Hs Code.:

Synonyms:rac-N-<2-benzyloxy-β-(4-benzyloxyphenyl)-3-methoxyphenethyl>-N-methylformamide

Suppliers and Price of rac-N-<2-benzyloxy-β-(4-benzyloxyphenyl)-3-methoxyphenethyl>-N-methylformamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of rac-N-<2-benzyloxy-β-(4-benzyloxyphenyl)-3-methoxyphenethyl>-N-methylformamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of rac-N-<2-benzyloxy-β-(4-benzyloxyphenyl)-3-methoxyphenethyl>-N-methylformamide

There total 14 articles about rac-N-<2-benzyloxy-β-(4-benzyloxyphenyl)-3-methoxyphenethyl>-N-methylformamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 97456-07-0
rac-2-benzyloxy-β-(4-benzyloxyphenyl)-3-methoxy-N-methylphenethylamine

: 2258-42-6
formyl acetic anhydride

: 97456-08-1
rac-N-<2-benzyloxy-β-(4-benzyloxyphenyl)-3-methoxyphenethyl>-N-methylformamide

Guidance literature:: In pyridine; at 0 ℃; for 0.666667h;

Reference yield:

: 4397-53-9
p-benzyloxybenzaldehyde

: 97456-08-1
rac-N-<2-benzyloxy-β-(4-benzyloxyphenyl)-3-methoxyphenethyl>-N-methylformamide

Guidance literature:: Multi-step reaction with 10 steps

1: 1.) NaH; 2.) DIBAL / 1.) THF, 0 deg C; 2.) toluene, 0 deg C

2: 34 percent / diethyl azodicarboxylate, triphenylphosphine

3: 75 percent / N,N-dimethylaniline / 0.83 h / Heating

4: 83 percent / K₂CO₃ / dimethylformamide / 9 h / 80 °C

5: 1.) O₃; 2.) sodium borohydride / 1.) MeOH, CH₂Cl₂, -78 deg C, 12 min; 2.) -78 deg C to r.t.

6: 86 percent / diethyl azodicarboxylate, triphenylphosphine

7: 96 percent / hydrazine hydrate / ethanol / 2.5 h / Heating

8: 90 percent / 0.75 h / 0 deg C to r.t.

9: 89 percent / lithium aluminum hydride / tetrahydrofuran / 3 h / Heating

10: 85 percent / 1 h / 0 deg C to r.t.

With sodium tetrahydroborate; lithium aluminium tetrahydride; sodium hydride; diisobutylaluminium hydride; potassium carbonate; ozone; hydrazine hydrate; N,N-dimethyl-aniline; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; ethanol; N,N-dimethyl-formamide;
DOI:10.1246/cl.1985.505

Reference yield:

: 97456-01-4
rac-6-(4-benzyloxy-α-vinylbenzyl)guiacol

: 97456-08-1
rac-N-<2-benzyloxy-β-(4-benzyloxyphenyl)-3-methoxyphenethyl>-N-methylformamide

Guidance literature:: Multi-step reaction with 7 steps

1: 83 percent / K₂CO₃ / dimethylformamide / 9 h / 80 °C

2: 1.) O₃; 2.) sodium borohydride / 1.) MeOH, CH₂Cl₂, -78 deg C, 12 min; 2.) -78 deg C to r.t.

3: 86 percent / diethyl azodicarboxylate, triphenylphosphine

4: 96 percent / hydrazine hydrate / ethanol / 2.5 h / Heating

5: 90 percent / 0.75 h / 0 deg C to r.t.

6: 89 percent / lithium aluminum hydride / tetrahydrofuran / 3 h / Heating

7: 85 percent / 1 h / 0 deg C to r.t.

With sodium tetrahydroborate; lithium aluminium tetrahydride; potassium carbonate; ozone; hydrazine hydrate; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; ethanol; N,N-dimethyl-formamide;
DOI:10.1246/cl.1985.505