(3S,E)-3-((4-methoxybenzyl)oxy)-3-methyl-11-((tetrahydro-2H-pyran-2-yl)oxy)undec-9-en-4-ol

Base Information

Chemical Name:(3S,E)-3-((4-methoxybenzyl)oxy)-3-methyl-11-((tetrahydro-2H-pyran-2-yl)oxy)undec-9-en-4-ol
CAS No.:1354575-56-6
Molecular Formula:C₂₅H₄₀O₅
Molecular Weight:420.59
Hs Code.:

Synonyms:(3S,E)-3-((4-methoxybenzyl)oxy)-3-methyl-11-((tetrahydro-2H-pyran-2-yl)oxy)undec-9-en-4-ol

Suppliers and Price of (3S,E)-3-((4-methoxybenzyl)oxy)-3-methyl-11-((tetrahydro-2H-pyran-2-yl)oxy)undec-9-en-4-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (3S,E)-3-((4-methoxybenzyl)oxy)-3-methyl-11-((tetrahydro-2H-pyran-2-yl)oxy)undec-9-en-4-ol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (3S,E)-3-((4-methoxybenzyl)oxy)-3-methyl-11-((tetrahydro-2H-pyran-2-yl)oxy)undec-9-en-4-ol

There total 12 articles about (3S,E)-3-((4-methoxybenzyl)oxy)-3-methyl-11-((tetrahydro-2H-pyran-2-yl)oxy)undec-9-en-4-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 1354575-55-5
(S)-2-((4-methoxybenzyl)oxy)-2-methylbutanal

: 1354575-51-1
(E)-2-((7-iodohept-2-en-1-yl)oxy)tetrahydro-2H-pyran

: 1354575-56-6
(3S,E)-3-((4-methoxybenzyl)oxy)-3-methyl-11-((tetrahydro-2H-pyran-2-yl)oxy)undec-9-en-4-ol

Guidance literature:: (E)-2-((7-iodohept-2-en-1-yl)oxy)tetrahydro-2H-pyran; With tert.-butyl lithium; In diethyl ether; pentane; at -78 ℃; for 0.25h; Inert atmosphere;

(S)-2-((4-methoxybenzyl)oxy)-2-methylbutanal; In diethyl ether; pentane; at -78 - 0 ℃; Inert atmosphere;

With ammonium chloride; In diethyl ether; water; pentane; at 0 ℃; Inert atmosphere;
DOI:10.1038/ja.2011.90

Reference yield:

: 1310814-64-2
(E)-7-((tetrahydro-2H-pyran-2-yl)oxy)hept-5-en-1-ol

: 1354575-56-6
(3S,E)-3-((4-methoxybenzyl)oxy)-3-methyl-11-((tetrahydro-2H-pyran-2-yl)oxy)undec-9-en-4-ol

Guidance literature:: Multi-step reaction with 3 steps

1.1: trimethylamine hydrochloride; triethylamine / dichloromethane / 3 h / 0 - 20 °C / Inert atmosphere

2.1: sodium iodide / acetone / 8.5 h / Inert atmosphere; Reflux

3.1: tert.-butyl lithium / diethyl ether; pentane / 0.25 h / -78 °C / Inert atmosphere

3.2: -78 - 0 °C / Inert atmosphere

3.3: 0 °C / Inert atmosphere

With tert.-butyl lithium; trimethylamine hydrochloride; triethylamine; sodium iodide; In diethyl ether; dichloromethane; acetone; pentane;
DOI:10.1038/ja.2011.90

Reference yield:

: C₁₈H₃₆O₃Si

: 1354575-56-6
(3S,E)-3-((4-methoxybenzyl)oxy)-3-methyl-11-((tetrahydro-2H-pyran-2-yl)oxy)undec-9-en-4-ol

Guidance literature:: Multi-step reaction with 4 steps

1.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 4.5 h / 20 °C / Inert atmosphere

2.1: trimethylamine hydrochloride; triethylamine / dichloromethane / 3 h / 0 - 20 °C / Inert atmosphere

3.1: sodium iodide / acetone / 8.5 h / Inert atmosphere; Reflux

4.1: tert.-butyl lithium / diethyl ether; pentane / 0.25 h / -78 °C / Inert atmosphere

4.2: -78 - 0 °C / Inert atmosphere

4.3: 0 °C / Inert atmosphere

With tetrabutyl ammonium fluoride; tert.-butyl lithium; trimethylamine hydrochloride; triethylamine; sodium iodide; In tetrahydrofuran; diethyl ether; dichloromethane; acetone; pentane;
DOI:10.1038/ja.2011.90