methyl 3-(1-{[1-(3-ethoxyphenyl)-2-(2-fluoro-4-methylphenyl)-1H-imidazol-4-yl]carbonyl}piperidin-4-yl)-1-naphthoate trifluoroacetate

Base Information

Chemical Name:methyl 3-(1-{[1-(3-ethoxyphenyl)-2-(2-fluoro-4-methylphenyl)-1H-imidazol-4-yl]carbonyl}piperidin-4-yl)-1-naphthoate trifluoroacetate
CAS No.:954398-65-3
Molecular Formula:C₂HF₃O₂*C₃₆H₃₄FN₃O₄
Molecular Weight:705.706
Hs Code.:

Synonyms:methyl 3-(1-{[1-(3-ethoxyphenyl)-2-(2-fluoro-4-methylphenyl)-1H-imidazol-4-yl]carbonyl}piperidin-4-yl)-1-naphthoate trifluoroacetate

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Chemical Property of methyl 3-(1-{[1-(3-ethoxyphenyl)-2-(2-fluoro-4-methylphenyl)-1H-imidazol-4-yl]carbonyl}piperidin-4-yl)-1-naphthoate trifluoroacetate

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Technology Process of methyl 3-(1-{[1-(3-ethoxyphenyl)-2-(2-fluoro-4-methylphenyl)-1H-imidazol-4-yl]carbonyl}piperidin-4-yl)-1-naphthoate trifluoroacetate

There total 1 articles about methyl 3-(1-{[1-(3-ethoxyphenyl)-2-(2-fluoro-4-methylphenyl)-1H-imidazol-4-yl]carbonyl}piperidin-4-yl)-1-naphthoate trifluoroacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 954382-71-9
1-(3-ethoxyphenyl)-2-(2-fluoro-4-methylphenyl)-1H-imidazole-4-carboxylic acid

: 954398-61-9
methyl 3-piperidin-4-yl-1-naphthoate

: 76-05-1
trifluoroacetic acid

: 954398-65-3
methyl 3-(1-{[1-(3-ethoxyphenyl)-2-(2-fluoro-4-methylphenyl)-1H-imidazol-4-yl]carbonyl}piperidin-4-yl)-1-naphthoate trifluoroacetate

Guidance literature:: 1-(3-ethoxyphenyl)-2-(2-fluoro-4-methylphenyl)-1H-imidazole-4-carboxylic acid; With 1-methyl-1H-imidazole; methanesulfonyl chloride; In dichloromethane; at -78 - 20 ℃; for 0.333333h;

methyl 3-piperidin-4-yl-1-naphthoate; In dichloromethane; at 0 - 20 ℃; for 16h;

trifluoroacetic acid; In water; acetonitrile;

Reference yield:

: 954398-65-3
methyl 3-(1-{[1-(3-ethoxyphenyl)-2-(2-fluoro-4-methylphenyl)-1H-imidazol-4-yl]carbonyl}piperidin-4-yl)-1-naphthoate trifluoroacetate

: 76-05-1
trifluoroacetic acid

: 954398-48-2
3-(1-{[1-(3-ethoxyphenyl)-2-(2-fluoro-4-methylphenyl)-1H-imidazol-4-yl]carbonyl}piperidin-4-yl)-1-naphthoic acid trifluoroacetate

Guidance literature:: methyl 3-(1-{[1-(3-ethoxyphenyl)-2-(2-fluoro-4-methylphenyl)-1H-imidazol-4-yl]carbonyl}piperidin-4-yl)-1-naphthoate trifluoroacetate; With potassium trimethylsilonate; In tetrahydrofuran; at 20 ℃; for 16h;

trifluoroacetic acid; In water; acetonitrile;