C₉H₉BrF₂O₂

Base Information

• Chemical Name: C₉H₉BrF₂O₂
• CAS No.: 853771-74-1
• Molecular Formula: C₉H₉BrF₂O₂
• Molecular Weight: 267.07
• Mol file: 853771-74-1.mol

Synonyms:C₉H₉BrF₂O₂

Chemical Property of C₉H₉BrF₂O₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₉H₉BrF₂O₂

There total 2 articles about C₉H₉BrF₂O₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

[4-(difluoromethoxy)-3-methoxyphenyl]methanol (199854-38-1) → C9H9BrF2O2 (853771-74-1)

Guidance literature:

With phosphorus tribromide; In dichloromethane; at 0 ℃; for 0.5h;

DOI:10.1016/j.ejmech.2012.07.010

Reference yield:

4-(difluoromethoxy)-3-methoxybenzaldehyde (162401-70-9) → C9H9BrF2O2 (853771-74-1)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium tetrahydroborate / dichloromethane / 0.5 h / 20 °C

2: phosphorus tribromide / dichloromethane / 0.5 h / 0 °C

With sodium tetrahydroborate; phosphorus tribromide; In dichloromethane;

DOI:10.1016/j.ejmech.2012.07.010

Reference yield:

tert-butyl 3-(tert-butoxycarbonyl)aminomethyl-4-(hydroxyimino)pyrrolidine-1-carboxylate (175463-36-2) + C9H9BrF2O2 (853771-74-1) → C24H35F2N3O7 (1400793-18-1)

Guidance literature:

C₉H₉BrF₂O₂; With sodium hydroxide; In dichloromethane; at 20 ℃; for 0.0833333h;

tert-butyl 3-(tert-butoxycarbonyl)aminomethyl-4-(hydroxyimino)pyrrolidine-1-carboxylate; In dichloromethane; at 20 ℃;

DOI:10.1016/j.ejmech.2012.07.010

upstream raw materials:

[4-(difluoromethoxy)-3-methoxyphenyl]methanol

4-(difluoromethoxy)-3-methoxybenzaldehyde

Downstream raw materials:

7-[3-(benzylideneamino)methyl-4-(4'-difluoromethxoy-3'-methxoybenzyloxyimino)pyrrolidin-1-yl]-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid

C₂₄H₃₅F₂N₃O₇

Refernces