N-9-fluorenylmethoxycarbonyl-L-alanyl-O-trityl-L-serylglycine benzyl ester

Base Information

Chemical Name:N-9-fluorenylmethoxycarbonyl-L-alanyl-O-trityl-L-serylglycine benzyl ester
CAS No.:171820-85-2
Molecular Formula:C₄₉H₄₅N₃O₇
Molecular Weight:787.912
Hs Code.:

Synonyms:N-9-fluorenylmethoxycarbonyl-L-alanyl-O-trityl-L-serylglycine benzyl ester

Suppliers and Price of N-9-fluorenylmethoxycarbonyl-L-alanyl-O-trityl-L-serylglycine benzyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-9-fluorenylmethoxycarbonyl-L-alanyl-O-trityl-L-serylglycine benzyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-9-fluorenylmethoxycarbonyl-L-alanyl-O-trityl-L-serylglycine benzyl ester

There total 3 articles about N-9-fluorenylmethoxycarbonyl-L-alanyl-O-trityl-L-serylglycine benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 35661-39-3,136132-75-7
N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine

: 171820-84-1
O-trityl-L-serylglycine benzyl ester

: 171820-85-2
N-9-fluorenylmethoxycarbonyl-L-alanyl-O-trityl-L-serylglycine benzyl ester

Guidance literature:: With benzotriazol-1-ol; 2`,3`-dideoxycytidine; In dichloromethane; at -10 - 20 ℃; for 16h;
DOI:10.1016/0008-6215(95)00097-D

Reference yield:

: 171820-83-0
N,O-ditrityl-L-serylglycine benzyl ester

: 171820-85-2
N-9-fluorenylmethoxycarbonyl-L-alanyl-O-trityl-L-serylglycine benzyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 63 percent / CF₃CO₂H / CH₂Cl₂ / 0.17 h

2: 87 percent / DDC, HOBT / CH₂Cl₂ / 16 h / -10 - 20 °C

With benzotriazol-1-ol; 2`,3`-dideoxycytidine; trifluoroacetic acid; In dichloromethane;
DOI:10.1016/0008-6215(95)00097-D

Reference yield:

: N,O-ditrityl-L-serine triethylamine salt

: 171820-85-2
N-9-fluorenylmethoxycarbonyl-L-alanyl-O-trityl-L-serylglycine benzyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 99 percent / DCC, HOBT / CH₂Cl₂

2: 63 percent / CF₃CO₂H / CH₂Cl₂ / 0.17 h

3: 87 percent / DDC, HOBT / CH₂Cl₂ / 16 h / -10 - 20 °C

With benzotriazol-1-ol; dicyclohexyl-carbodiimide; 2`,3`-dideoxycytidine; trifluoroacetic acid; In dichloromethane;
DOI:10.1016/0008-6215(95)00097-D