2-[(2-amino-1,6-dihydro-6-oxopurin-9-yl)methyloxy]-3-hydroxypropyl 2'-(S)-azido-3'-methylbutanoate

Base Information

Chemical Name:2-[(2-amino-1,6-dihydro-6-oxopurin-9-yl)methyloxy]-3-hydroxypropyl 2'-(S)-azido-3'-methylbutanoate
CAS No.:1219792-38-7
Molecular Formula:C₁₄H₂₀N₈O₅
Molecular Weight:380.363
Hs Code.:

Synonyms:2-[(2-amino-1,6-dihydro-6-oxopurin-9-yl)methyloxy]-3-hydroxypropyl 2'-(S)-azido-3'-methylbutanoate

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Chemical Property of 2-[(2-amino-1,6-dihydro-6-oxopurin-9-yl)methyloxy]-3-hydroxypropyl 2'-(S)-azido-3'-methylbutanoate

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Technology Process of 2-[(2-amino-1,6-dihydro-6-oxopurin-9-yl)methyloxy]-3-hydroxypropyl 2'-(S)-azido-3'-methylbutanoate

There total 1 articles about 2-[(2-amino-1,6-dihydro-6-oxopurin-9-yl)methyloxy]-3-hydroxypropyl 2'-(S)-azido-3'-methylbutanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 34.5%

: 1219792-39-8
2-(2-amino-1,6-dihydro-6-oxopurin-9-yl)methoxy-1,3-bis-1'-propyl-(2'S)-azido-3'-methylbutanoate

: 1219792-38-7
2-[(2-amino-1,6-dihydro-6-oxopurin-9-yl)methyloxy]-3-hydroxypropyl 2'-(S)-azido-3'-methylbutanoate

: 82410-32-0
ganciclovir

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In methanol; at 20 ℃; for 14h;
DOI:10.3998/ark.5550190.0012.215

Reference yield: 70.6%

: 1219792-38-7
2-[(2-amino-1,6-dihydro-6-oxopurin-9-yl)methyloxy]-3-hydroxypropyl 2'-(S)-azido-3'-methylbutanoate

: 175865-59-5
valganciclovir hydrochloride

Guidance literature:: With hydrogenchloride; palladium 10% on activated carbon; hydrogen; In methanol; water; for 2h; under 2942.29 Torr; Autoclave;
DOI:10.3998/ark.5550190.0012.215