3-tert-butyl-2-hydroxybenzhydrol

Base Information

• Chemical Name: 3-tert-butyl-2-hydroxybenzhydrol
• CAS No.: 911001-84-8
• Molecular Formula: C₁₇H₂₀O₂
• Molecular Weight: 256.345
• Mol file: 911001-84-8.mol

Synonyms:3-tert-butyl-2-hydroxybenzhydrol

Chemical Property of 3-tert-butyl-2-hydroxybenzhydrol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-tert-butyl-2-hydroxybenzhydrol

There total 2 articles about 3-tert-butyl-2-hydroxybenzhydrol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

bromobenzene (108-86-1,52753-63-6) + 3-tert-butyl-2-hydroxybenzaldehyde (24623-65-2) → 3-tert-butyl-2-hydroxybenzhydrol (911001-84-8)

Guidance literature:

bromobenzene; With magnesium; In diethyl ether; for 1.5h; Reflux;

3-tert-butyl-2-hydroxybenzaldehyde; In diethyl ether; at 0 ℃; for 2h; Reflux;

DOI:10.1002/ejoc.201101578

Reference yield:

3-tert-butyl-2-hydroxybenzaldehyde (24623-65-2) → 3-tert-butyl-2-hydroxybenzhydrol (911001-84-8)

Guidance literature:

DOI:10.1021/jo060964u

Reference yield: 83.0%

3-tert-butyl-2-hydroxybenzhydrol (911001-84-8) → (3-(tert-butyl)-2-hydroxyphenyl)(phenyl)methanone (24248-99-5)

Guidance literature:

With ethene; palladium on activated charcoal; In acetonitrile; at 80 ℃; for 7h; under 760 Torr;

DOI:10.1021/jo060964u

upstream raw materials:

3-tert-butyl-2-hydroxybenzaldehyde

bromobenzene

Downstream raw materials:

(3-(tert-butyl)-2-hydroxyphenyl)(phenyl)methanone

3-acetyl-8-tert-butyl-4-phenyl-2H-chromen-2-one