[(1S,2R)-1-Benzyl-3-((3S,4aS,8aS)-3-tert-butylcarbamoyl-octahydro-isoquinolin-2-yl)-2-hydroxy-propyl]-carbamic acid (3R,4S)-4-methyl-tetrahydro-thiophen-3-yl ester

Base Information

Chemical Name:[(1S,2R)-1-Benzyl-3-((3S,4aS,8aS)-3-tert-butylcarbamoyl-octahydro-isoquinolin-2-yl)-2-hydroxy-propyl]-carbamic acid (3R,4S)-4-methyl-tetrahydro-thiophen-3-yl ester
CAS No.:1054737-19-7
Molecular Formula:C₃₀H₄₇N₃O₄S
Molecular Weight:545.787
Hs Code.:

[(1S,2R)-1-Benzyl-3-((3S,4aS,8aS)-3-tert-butylcarbamoyl-octahydro-isoquinolin-2-yl)-2-hydroxy-propyl]-carbamic acid (3R,4S)-4-methyl-tetrahydro-thiophen-3-yl ester

Synonyms:[(1S,2R)-1-Benzyl-3-((3S,4aS,8aS)-3-tert-butylcarbamoyl-octahydro-isoquinolin-2-yl)-2-hydroxy-propyl]-carbamic acid (3R,4S)-4-methyl-tetrahydro-thiophen-3-yl ester

Suppliers and Price of [(1S,2R)-1-Benzyl-3-((3S,4aS,8aS)-3-tert-butylcarbamoyl-octahydro-isoquinolin-2-yl)-2-hydroxy-propyl]-carbamic acid (3R,4S)-4-methyl-tetrahydro-thiophen-3-yl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of [(1S,2R)-1-Benzyl-3-((3S,4aS,8aS)-3-tert-butylcarbamoyl-octahydro-isoquinolin-2-yl)-2-hydroxy-propyl]-carbamic acid (3R,4S)-4-methyl-tetrahydro-thiophen-3-yl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of [(1S,2R)-1-Benzyl-3-((3S,4aS,8aS)-3-tert-butylcarbamoyl-octahydro-isoquinolin-2-yl)-2-hydroxy-propyl]-carbamic acid (3R,4S)-4-methyl-tetrahydro-thiophen-3-yl ester

There total 10 articles about [(1S,2R)-1-Benzyl-3-((3S,4aS,8aS)-3-tert-butylcarbamoyl-octahydro-isoquinolin-2-yl)-2-hydroxy-propyl]-carbamic acid (3R,4S)-4-methyl-tetrahydro-thiophen-3-yl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 136465-89-9
(2S)-2-[1'(S)-1-azido-2-phenylethyl]oxirane

: 1054737-19-7
[(1S,2R)-1-Benzyl-3-((3S,4aS,8aS)-3-tert-butylcarbamoyl-octahydro-isoquinolin-2-yl)-2-hydroxy-propyl]-carbamic acid (3R,4S)-4-methyl-tetrahydro-thiophen-3-yl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 84 percent / propan-2-ol / 80 °C

2: H₂, AcOH / 10percent Pd/C / methanol; tetrahydrofuran

3: CH₂Cl₂ / 12 h / 24 °C

With hydrogen; acetic acid; palladium on activated charcoal; In tetrahydrofuran; methanol; dichloromethane; isopropyl alcohol;
DOI:10.1021/jm00034a016

Reference yield:

: 128019-40-9,149510-73-6,136465-81-1,168899-60-3
(3S,4aS,8aS)-N-tert-butyl-decahydroisoquinoline-3-carboxamide

: 1054737-19-7
[(1S,2R)-1-Benzyl-3-((3S,4aS,8aS)-3-tert-butylcarbamoyl-octahydro-isoquinolin-2-yl)-2-hydroxy-propyl]-carbamic acid (3R,4S)-4-methyl-tetrahydro-thiophen-3-yl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 84 percent / propan-2-ol / 80 °C

2: H₂, AcOH / 10percent Pd/C / methanol; tetrahydrofuran

3: CH₂Cl₂ / 12 h / 24 °C

With hydrogen; acetic acid; palladium on activated charcoal; In tetrahydrofuran; methanol; dichloromethane; isopropyl alcohol;
DOI:10.1021/jm00034a016

Reference yield:

: 136465-90-2
N-tert-butyl-2-<2(R)-hydroxy-4-phenyl-3(S)-azidobutyl>decahydro(4aS,8aS)-isoquinoline-3(S)-carboxamide

: 1054737-19-7
[(1S,2R)-1-Benzyl-3-((3S,4aS,8aS)-3-tert-butylcarbamoyl-octahydro-isoquinolin-2-yl)-2-hydroxy-propyl]-carbamic acid (3R,4S)-4-methyl-tetrahydro-thiophen-3-yl ester

Guidance literature:: Multi-step reaction with 2 steps

1: H₂, AcOH / 10percent Pd/C / methanol; tetrahydrofuran

2: CH₂Cl₂ / 12 h / 24 °C

With hydrogen; acetic acid; palladium on activated charcoal; In tetrahydrofuran; methanol; dichloromethane;
DOI:10.1021/jm00034a016