N-(2-(difluoro(4-fluorophenyl)methyl)-4-(5-methyl-1H-pyrazol-3-amino)pyrrolo[2,1-f][1,2,4]triazin-6-yl)-3-morpholinopropanamide

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Chemical Name:N-(2-(difluoro(4-fluorophenyl)methyl)-4-(5-methyl-1H-pyrazol-3-amino)pyrrolo[2,1-f][1,2,4]triazin-6-yl)-3-morpholinopropanamide
CAS No.:1204244-87-0
Molecular Formula:C₂₄H₂₅F₃N₈O₂
Molecular Weight:514.51
Hs Code.:

Synonyms:N-(2-(difluoro(4-fluorophenyl)methyl)-4-(5-methyl-1H-pyrazol-3-amino)pyrrolo[2,1-f][1,2,4]triazin-6-yl)-3-morpholinopropanamide

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Chemical Property of N-(2-(difluoro(4-fluorophenyl)methyl)-4-(5-methyl-1H-pyrazol-3-amino)pyrrolo[2,1-f][1,2,4]triazin-6-yl)-3-morpholinopropanamide

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Technology Process of N-(2-(difluoro(4-fluorophenyl)methyl)-4-(5-methyl-1H-pyrazol-3-amino)pyrrolo[2,1-f][1,2,4]triazin-6-yl)-3-morpholinopropanamide

There total 1 articles about N-(2-(difluoro(4-fluorophenyl)methyl)-4-(5-methyl-1H-pyrazol-3-amino)pyrrolo[2,1-f][1,2,4]triazin-6-yl)-3-morpholinopropanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 10.0%

: 4497-04-5
3-morpholin-4-ylpropionic acid

: 1204245-57-7
2-(difluoro(4-fluorophenyl)methyl)-N-(5-methyl-1H-pyrazol-3-yl)-6-nitropyrrolo[2,1-f][1,2,4]triazin-4-amine

: 1204244-87-0
N-(2-(difluoro(4-fluorophenyl)methyl)-4-(5-methyl-1H-pyrazol-3-amino)pyrrolo[2,1-f][1,2,4]triazin-6-yl)-3-morpholinopropanamide

: 1204244-89-2
N-(5-chloro-2-(difluoro(4-fluorophenyl)methyl)-4-(5-methyl-1H-pyrazol-3-ylamino)pyrrolo[2,1-f][1,2,4]triazin-6-yl)-3-morpholinopropanamide

Guidance literature:: 2-(difluoro(4-fluorophenyl)methyl)-N-(5-methyl-1H-pyrazol-3-yl)-6-nitropyrrolo[2,1-f][1,2,4]triazin-4-amine; With hydrogenchloride; hydrogen; palladium 10% on activated carbon; In methanol; for 1.5h;

3-morpholin-4-ylpropionic acid; With N-ethyl-N,N-diisopropylamine; HATU; In N,N-dimethyl-formamide; at 20 ℃;