13-cis-retinoyl chloride

Base Information

• Chemical Name: 13-cis-retinoyl chloride
• CAS No.: 73174-99-9
• Molecular Formula: C₂₀H₂₇ClO
• Molecular Weight: 318.887
• Mol file: 73174-99-9.mol

Synonyms:13-cis-retinoyl chloride

Chemical Property of 13-cis-retinoyl chloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 13-cis-retinoyl chloride

There total 1 articles about 13-cis-retinoyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

13-cis-retinoic acid (4759-48-2) → 13-cis-retinoyl chloride (73174-99-9)

Guidance literature:

With thionyl chloride; triethylamine; In benzene; at 20 ℃; for 0.5h;

Reference yield: 91.0%

L-Leucine ethyl ester (2743-60-4,75023-21-1) + 13-cis-retinoyl chloride (73174-99-9) → N-(13-cis-retinoyl)-L-leucine ethyl ester (110769-91-0)

Guidance literature:

In N,N-dimethyl-formamide; benzene; for 1h;

DOI:10.1021/jm00396a031

Reference yield: 83.0%

DL-phenylalanine methyl ester (15028-44-1) + 13-cis-retinoyl chloride (73174-99-9) → N-(13-cis-retinoyl)-DL-phenylalanine methyl ester (110770-00-8)

Guidance literature:

In N,N-dimethyl-formamide; benzene; for 1h;

DOI:10.1021/jm00396a031

upstream raw materials:

13-cis-retinoic acid

Downstream raw materials:

N-(13-cis-retinoyl)-L-alanine ethyl ester

N-(13-cis-retinoyl)-L-leucine ethyl ester

N-(13-cis-retinoyl)-DL-phenylalanine methyl ester

(2Z,4E,6E,8E)-N-(4-hydroxyphenyl)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenamide