Urea, N-cycloheptyl-N-((4-(4-fluorophenoxy)phenyl)methyl)-N'-(6-methyl-2,4-bis(methylsulfonyl)-3-pyridinyl)-

Base Information

Chemical Name:Urea, N-cycloheptyl-N-((4-(4-fluorophenoxy)phenyl)methyl)-N'-(6-methyl-2,4-bis(methylsulfonyl)-3-pyridinyl)-
CAS No.:215589-63-2
Molecular Formula:C₂₉H₃₄FN₃O₆S₂
Molecular Weight:603.736
Hs Code.:
UNII:1U8UW770Z6
Nikkaji Number:J1.028.393K
Wikidata:Q27252896
ChEMBL ID:CHEMBL138323

Synonyms:FR 190809;FR-190809;N-cycloheptyl-N-(4-(4-fluorophenoxy)-benzyl)-N'-(2,4-bis(methylsulfonyl)-6-methylpyridin-3-yl)urea

Suppliers and Price of Urea, N-cycloheptyl-N-((4-(4-fluorophenoxy)phenyl)methyl)-N'-(6-methyl-2,4-bis(methylsulfonyl)-3-pyridinyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of Urea, N-cycloheptyl-N-((4-(4-fluorophenoxy)phenyl)methyl)-N'-(6-methyl-2,4-bis(methylsulfonyl)-3-pyridinyl)-

Chemical Property:

XLogP3:5.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:8
Exact Mass:603.18730632
Heavy Atom Count:41
Complexity:1060

Purity/Quality:: >98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC(=C(C(=N1)S(=O)(=O)C)NC(=O)N(CC2=CC=C(C=C2)OC3=CC=C(C=C3)F)C4CCCCCC4)S(=O)(=O)C

Technology Process of Urea, N-cycloheptyl-N-((4-(4-fluorophenoxy)phenyl)methyl)-N'-(6-methyl-2,4-bis(methylsulfonyl)-3-pyridinyl)-

There total 1 articles about Urea, N-cycloheptyl-N-((4-(4-fluorophenoxy)phenyl)methyl)-N'-(6-methyl-2,4-bis(methylsulfonyl)-3-pyridinyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 179054-51-4
1-cycloheptyl-1-[4-(4-fluoro-phenoxy)-benzyl]-3-(6-methyl-2,4-bis-methylsulfanyl-pyridin-3-yl)-urea

: 215589-63-2
3-(2,4-bis-methanesulfonyl-6-methyl-pyridin-3-yl)-1-cycloheptyl-1-[4-(4-fluoro-phenoxy)-benzyl]-urea

Guidance literature:: With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; for 72h; Ambient temperature;
DOI:10.1021/jm980399q

Reference yield: 47.0%

: 215589-63-2
3-(2,4-bis-methanesulfonyl-6-methyl-pyridin-3-yl)-1-cycloheptyl-1-[4-(4-fluoro-phenoxy)-benzyl]-urea

: 5188-07-8
sodium thiomethoxide

: 1-cycloheptyl-1-[4-(4-fluoro-phenoxy)-benzyl]-3-(2-methanesulfonyl-6-methyl-4-methylsulfanyl-pyridin-3-yl)-urea

Guidance literature:: In methanol; at 50 ℃; for 1h;
DOI:10.1021/jm980399q

Reference yield:

: 215589-63-2
3-(2,4-bis-methanesulfonyl-6-methyl-pyridin-3-yl)-1-cycloheptyl-1-[4-(4-fluoro-phenoxy)-benzyl]-urea

: N-cycloheptyl-N-<4-(4-fluorophenoxy)benzyl>-N'-<6-methyl-2-(methylsulfonyl)pyridin-3-yl>urea

Guidance literature:: Multi-step reaction with 2 steps

1: 47 percent / methanol / 1 h / 50 °C

2: 81 percent / Raney-Ni / ethanol / 0.25 h / Heating

With nickel; In methanol; ethanol;
DOI:10.1021/jm980399q