4-Chloro-2-methylbenzylamine

Base Information

Chemical Name:4-Chloro-2-methylbenzylamine
CAS No.:27917-11-9
Molecular Formula:C8H10ClN
Molecular Weight:155.627
Hs Code.:2921490090
European Community (EC) Number:674-024-0
DSSTox Substance ID:DTXSID50373998
Wikidata:Q81977540
Mol file:27917-11-9.mol

Synonyms:4-Chloro-2-methylbenzylamine;27917-11-9;(4-chloro-2-methylphenyl)methanamine;Benzenemethanamine,4-chloro-2-methyl-;Benzenemethanamine, 4-chloro-2-methyl-;SCHEMBL193074;DTXSID50373998;WTSJOJUKDNGALK-UHFFFAOYSA-N;CBA91711;MFCD00047932;AKOS006344927;FS-1534;(4-chloranyl-2-methyl-phenyl)methanamine;4-Chloro-2-methylbenzylamine, AldrichCPR;CS-0450584;FT-0638735;EN300-761435;A819242;3-(5,6-Dimethyl-1H-benzoimidazol-2-yl)-propionicacid

Suppliers and Price of 4-Chloro-2-methylbenzylamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-Chloro-2-methylbenzylamine
500mg
$ 75.00

SynQuest Laboratories
4-Chloro-2-methylbenzylamine
1 g
$ 85.00

SynQuest Laboratories
4-Chloro-2-methylbenzylamine
5 g
$ 203.00

Matrix Scientific
4-Chloro-2-methylbenzylamine
1g
$ 51.00

Matrix Scientific
4-Chloro-2-methylbenzylamine
5g
$ 174.00

Labseeker
(4-chloro-2-methylphenyl)methanamine 95
25g
$ 3208.00

Labseeker
(4-chloro-2-methylphenyl)methanamine 95
5g
$ 1717.00

Crysdot
(4-Chloro-2-methylphenyl)methanamine 95+%
1g
$ 340.00

Apolloscientific
4-Chloro-2-methylbenzylamine
5g
$ 370.00

Apolloscientific
4-Chloro-2-methylbenzylamine
1g
$ 95.00

Total 14 raw suppliers

Chemical Property of 4-Chloro-2-methylbenzylamine

Chemical Property:

Vapor Pressure:0.0332mmHg at 25°C
Refractive Index:1.558
Boiling Point:242.8 °C at 760 mmHg
PKA:9.03±0.10(Predicted)
Flash Point:115.9 °C
PSA：26.02000
Density:1.13 g/cm³
LogP:2.80740
Storage Temp.:2-8°C(protect from light)
XLogP3:2.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:155.0501770
Heavy Atom Count:10
Complexity:105

Purity/Quality:

97% ^*data from raw suppliers

4-Chloro-2-methylbenzylamine ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 34-41-37/38
Safety Statements: 26-36/37/39-39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C=CC(=C1)Cl)CN

Technology Process of 4-Chloro-2-methylbenzylamine

There total 5 articles about 4-Chloro-2-methylbenzylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 4-chloro-2-methylbenzaldehyde oxime

: 27917-11-9
(4-chloro-2-methylphenyl)methanamine

Guidance literature:: With acetic acid; zinc; at 60 ℃; for 2h;

Reference yield:

: 900505-06-8
2-(4-chloro-2-methyl-benzyl)-isoindole-1,3-dione

: 27917-11-9
(4-chloro-2-methylphenyl)methanamine

Guidance literature:: With hydrazine; In tetrahydrofuran; at 80 ℃; for 1h;
DOI:10.1016/j.bmcl.2006.04.009

Reference yield:

: 40137-29-9
2-methyl-4-chlorobenzaldehyde

: 27917-11-9
(4-chloro-2-methylphenyl)methanamine

Guidance literature:: Multi-step reaction with 3 steps

1: NaBH₄ / tetrahydrofuran / 1 h / 20 °C

2: Ph₃P; DIAD / tetrahydrofuran / 3 h / 20 °C

3: hydrazine / tetrahydrofuran / 1 h / 80 °C

With sodium tetrahydroborate; di-isopropyl azodicarboxylate; triphenylphosphine; hydrazine; In tetrahydrofuran; 2: Mitsunobu reaction;
DOI:10.1016/j.bmcl.2006.04.009