Technology Process of 3(R),4(R)-dimethyl-1,15,15,15-tetraphenyl-2,5,8,11,14-pentaoxadodecane
There total 2 articles about 3(R),4(R)-dimethyl-1,15,15,15-tetraphenyl-2,5,8,11,14-pentaoxadodecane which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 83 percent / pyridine / 3 h at 0 deg C and 14 h at r.t.
2: 98 percent / KOH / tetrahydrofuran / 3 h at 0 deg C and 7 h at r.t.
3: 1) NaH / 1) DMF, mineral oil, 10 min at r.t. and 2 h at 85 deg C, 2) DMF, 10 min at 0 deg C, 10 min at r.t. and 2 days at 85 deg C
With
pyridine; potassium hydroxide; sodium hydride;
In
tetrahydrofuran;
DOI:10.1021/jo00010a028
- Guidance literature:
-
With
sodium hydride;
Yield given. Multistep reaction;
1) DMF, mineral oil, 10 min at r.t. and 2 h at 85 deg C, 2) DMF, 10 min at 0 deg C, 10 min at r.t. and 2 days at 85 deg C;
DOI:10.1021/jo00010a028
- Guidance literature:
-
With
hydrogen;
palladium on activated charcoal;
In
ethanol;
for 96h;
under 760 Torr;
Ambient temperature;
DOI:10.1021/jo00010a028
