N-(3-chlorophenyl)-N-methylcarbamothioyl chloride

Base Information

Chemical Name:N-(3-chlorophenyl)-N-methylcarbamothioyl chloride
CAS No.:83508-61-6
Molecular Formula:C₈H₇Cl₂NS
Molecular Weight:220.122
Hs Code.:
European Community (EC) Number:671-400-6
DSSTox Substance ID:DTXSID90374040
Wikidata:Q82162498

Synonyms:83508-61-6;N-(3-Chlorophenyl)-N-methyl-thiocarbamoyl chloride;N-(3-chlorophenyl)-N-methylcarbamothioyl chloride;Carbamothioic chloride,(3-chlorophenyl)methyl- (9CI);n-(3-chlorophenyl)-n-methylthiocarbamoyl chloride;DTXSID90374040;MFCD03093838;AKOS037652949;FS-5358;A840592;N-(3-chlorophenyl)-N-methyl-carbamothioyl chloride;3-CHLORO-N-(CHLOROMETHANETHIOYL)-N-METHYLANILINE

Suppliers and Price of N-(3-chlorophenyl)-N-methylcarbamothioyl chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Oakwood
N-(3-Chlorophenyl)-N-methyl-thiocarbamoylchloride 98%
5g
$ 600.00

Oakwood
N-(3-Chlorophenyl)-N-methyl-thiocarbamoylchloride 98%
1g
$ 200.00

American Custom Chemicals Corporation
N-(3-CHLOROPHENYL)-N-METHYL-THIOCARBAMOYL CHLORIDE 95.00%
5G
$ 1042.97

American Custom Chemicals Corporation
N-(3-CHLOROPHENYL)-N-METHYL-THIOCARBAMOYL CHLORIDE 95.00%
1G
$ 692.49

American Custom Chemicals Corporation
N-(3-CHLOROPHENYL)-N-METHYL-THIOCARBAMOYL CHLORIDE 95.00%
250MG
$ 168.00

Total 7 raw suppliers

Chemical Property of N-(3-chlorophenyl)-N-methylcarbamothioyl chloride

Chemical Property:

PSA：35.33000
LogP:3.29990
XLogP3:3.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:218.9676258
Heavy Atom Count:12
Complexity:174

Purity/Quality:

97% ^*data from raw suppliers

N-(3-Chlorophenyl)-N-methyl-thiocarbamoylchloride 98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(C1=CC(=CC=C1)Cl)C(=S)Cl

Technology Process of N-(3-chlorophenyl)-N-methylcarbamothioyl chloride

There total 1 articles about N-(3-chlorophenyl)-N-methylcarbamothioyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 463-71-8
thiophosgene

: 7006-52-2
3-chloro-N-methylaniline

: 83508-61-6
3-chlorophenyl(methyl)carbamothioic chloride

Guidance literature:: With triethylamine; Inert atmosphere;
DOI:10.1021/ol5002522

Reference yield:

: 83508-61-6
3-chlorophenyl(methyl)carbamothioic chloride

: (S)-2-(3-chlorophenyl)but-3-ene-2-thiol

: 1558812-30-8
(R)-2-(3-chlorophenyl)but-3-ene-2-thiol

Guidance literature:: Multi-step reaction with 4 steps

1.1: sodium hydride; sodium iodide / tetrahydrofuran / Inert atmosphere

2.1: toluene / Reflux; Inert atmosphere

3.1: lithium diisopropyl amide; lithium chloride / tetrahydrofuran / 2 h / -78 °C / Inert atmosphere

3.2: 0.17 h / -78 °C / Inert atmosphere

4.1: sodium ethanolate / ethanol; diethyl ether / 0.75 h / 0 °C / Inert atmosphere

With sodium ethanolate; sodium hydride; sodium iodide; lithium chloride; lithium diisopropyl amide; In tetrahydrofuran; diethyl ether; ethanol; toluene;
DOI:10.1021/ol5002522

Reference yield:

: 83508-61-6
3-chlorophenyl(methyl)carbamothioic chloride

: 1558811-06-5
(R)-S-but-3-en-2-yl 3-chlorophenyl(methyl)carbamothioate

: (S)-S-but-3-en-2-yl 3-chlorophenyl(methyl)carbamothioate

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydride; sodium iodide / tetrahydrofuran / Inert atmosphere

2: [(Sp,R)-COP-Cl]2 / tetrahydrofuran / 20 °C / Inert atmosphere

With [(Sp,R)-COP-Cl]2; sodium hydride; sodium iodide; In tetrahydrofuran;
DOI:10.1021/ol5002522