2-Phenyl-2-hydroxyethyl butyrate

Base Information

• Chemical Name: 2-Phenyl-2-hydroxyethyl butyrate
• CAS No.: 10522-04-0
• Molecular Formula: C₁₂H₁₆O₃
• Molecular Weight: 208.257
• Mol file: 10522-04-0.mol

Synonyms:2-Phenyl-2-hydroxyethyl butyrate

Chemical Property of 2-Phenyl-2-hydroxyethyl butyrate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of 2-Phenyl-2-hydroxyethyl butyrate

There total 3 articles about 2-Phenyl-2-hydroxyethyl butyrate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

phenylethane 1,2-diol (93-56-1) + 2,2,2-trifluoroethylbutyrate (371-27-7) → 2-Phenyl-2-hydroxyethyl butyrate (10522-04-0)

Guidance literature:

In acetone; at 42 - 45 ℃; porcine pancreas lipase;

DOI:10.1016/S0040-4020(01)89922-1

Reference yield:

styrene oxide (96-09-3) + butyric acid (107-92-6) → 2-hydroxy-1-phenylethyl butyrate + 2-Phenyl-2-hydroxyethyl butyrate (10522-04-0)

Guidance literature:

With graphite oxide; at 50 ℃; for 0.166667h; regioselective reaction;

DOI:10.2174/1570178616666190401194252

Reference yield:

2-Phenyl-2-acetoxyethyl butyrate → 2-Phenyl-2-hydroxyethyl butyrate (10522-04-0)

Guidance literature:

With butan-1-ol; In tetrahydrofuran; at 42 - 45 ℃; porcine pancreas lipase;

DOI:10.1016/S0040-4020(01)89922-1

upstream raw materials:

phenylethane 1,2-diol

2,2,2-trifluoroethylbutyrate

styrene oxide

butyric acid