(2R,4S,5R)-2-(α-diazobenzyl)-3,4-dimethyl-2-oxo-5-phenyl-1,3,2λ⁵-oxazaphospholidine

Base Information

• Chemical Name: (2R,4S,5R)-2-(α-diazobenzyl)-3,4-dimethyl-2-oxo-5-phenyl-1,3,2λ⁵-oxazaphospholidine
• CAS No.: 371160-38-2
• Molecular Formula: C₁₇H₁₈N₃O₂P
• Molecular Weight: 327.323

Synonyms:(2R,4S,5R)-2-(α-diazobenzyl)-3,4-dimethyl-2-oxo-5-phenyl-1,3,2λ⁵-oxazaphospholidine

Chemical Property of (2R,4S,5R)-2-(α-diazobenzyl)-3,4-dimethyl-2-oxo-5-phenyl-1,3,2λ⁵-oxazaphospholidine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2R,4S,5R)-2-(α-diazobenzyl)-3,4-dimethyl-2-oxo-5-phenyl-1,3,2λ⁵-oxazaphospholidine

There total 2 articles about (2R,4S,5R)-2-(α-diazobenzyl)-3,4-dimethyl-2-oxo-5-phenyl-1,3,2λ⁵-oxazaphospholidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 19.0%

(2R,4S,5R)-2-benzyl-3,4-dimethyl-2-oxo-5-phenyl-1,3,2λ5-oxazaphospholidine (278605-33-7) → (2S,4S,5R)-2-(Azido-phenyl-methyl)-3,4-dimethyl-5-phenyl-[1,3,2]oxazaphospholidine 2-oxide + (2R,4S,5R)-2-(α-diazobenzyl)-3,4-dimethyl-2-oxo-5-phenyl-1,3,2λ5-oxazaphospholidine (371160-38-2)

Guidance literature:

(2R,4S,5R)-2-benzyl-3,4-dimethyl-2-oxo-5-phenyl-1,3,2λ⁵-oxazaphospholidine; With lithium diisopropyl amide; In tetrahydrofuran; at -78 ℃; for 0.5h;

With p-nitrobenzenesulfonyl azide; In tetrahydrofuran; at -78 - 20 ℃;

DOI:10.1016/S0957-4166(01)00287-7

Reference yield: 1.7%

ephedrine (299-42-3,7009-81-6,90-83-5,6912-63-6) + O,O-diethyl α-diazobenzylphosphonate (19734-13-5) → (2R,4S,5R)-2-(α-diazobenzyl)-3,4-dimethyl-2-oxo-5-phenyl-1,3,2λ5-oxazaphospholidine (371160-38-2) + (2S,4S,5R)-2-(α-diazobenzyl)-3,4-dimethyl-2-oxo-5-phenyl-1,3,2λ5-oxazaphospholidine

Guidance literature:

O,O-diethyl α-diazobenzylphosphonate; With trimethylsilyl bromide; In dichloromethane;

With oxalyl dichloride; N,N-dimethyl-formamide; In N,N-dimethyl-formamide; for 0.5h;

ephedrine; With molecular sieve; triethylamine; In toluene;

DOI:10.1016/S0957-4166(01)00287-7

Reference yield: 58.0%

isopropyl alcohol (67-63-0,8013-70-5) + (2R,4S,5R)-2-(α-diazobenzyl)-3,4-dimethyl-2-oxo-5-phenyl-1,3,2λ5-oxazaphospholidine (371160-38-2) → (2R,4S,5R)-2-(α-isopropoxybenzyl)-3,4-dimethyl-2-oxo-5-phenyl-1,3,2λ5-oxazaphospholidine

Guidance literature:

dirhodium tetraacetate; In toluene; at 110 ℃; for 1h;

DOI:10.1016/S0957-4166(01)00287-7

upstream raw materials:

ephedrine

O,O-diethyl α-diazobenzylphosphonate

(2R,4S,5R)-2-benzyl-3,4-dimethyl-2-oxo-5-phenyl-1,3,2λ⁵-oxazaphospholidine

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 371160-38-2 (2R,4S,5R)-2-(α-diazobenzyl)-3,4-dimethyl-2-oxo-5-phenyl-1,3,2λ⁵-oxazaphospholidine

Send

Send

Metric Ton KG G Pound L ML

Send

Send