Benzyl 2(R)-[(4-Fluoro-3-methylphenyl)sulfonyl]amino-3(R)-cyclopentoxylbutyrate

Base Information

• Chemical Name: Benzyl 2(R)-[(4-Fluoro-3-methylphenyl)sulfonyl]amino-3(R)-cyclopentoxylbutyrate
• CAS No.: 629672-31-7
• Molecular Formula: C₂₃H₂₈FNO₅S
• Molecular Weight: 449.543

Synonyms:Benzyl 2(R)-[(4-Fluoro-3-methylphenyl)sulfonyl]amino-3(R)-cyclopentoxylbutyrate

Chemical Property of Benzyl 2(R)-[(4-Fluoro-3-methylphenyl)sulfonyl]amino-3(R)-cyclopentoxylbutyrate

Chemical Property:

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Technology Process of Benzyl 2(R)-[(4-Fluoro-3-methylphenyl)sulfonyl]amino-3(R)-cyclopentoxylbutyrate

There total 2 articles about Benzyl 2(R)-[(4-Fluoro-3-methylphenyl)sulfonyl]amino-3(R)-cyclopentoxylbutyrate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

benzyl 2(R)-amino-3(R)-cyclopentoxylbutyrate trifluoroacetate (629672-30-6) → Benzyl 2(R)-[(4-Fluoro-3-methylphenyl)sulfonyl]amino-3(R)-cyclopentoxylbutyrate (629672-31-7)

Guidance literature:

With dmap; 4-fluoro-3-methylbenzene-1-sulfonyl chloride; N-ethyl-N,N-diisopropylamine; In 1,3-dioxane; for 0.25h;

Reference yield:

→ Benzyl 2(R)-[(4-Fluoro-3-methylphenyl)sulfonyl]amino-3(R)-cyclopentoxylbutyrate (629672-31-7)

Guidance literature:

Reference yield:

Benzyl 2(R)-[(4-Fluoro-3-methylphenyl)sulfonyl]amino-3(R)-cyclopentoxylbutyrate (629672-31-7) → 2(R)-[(4-Fluoro-3-methylphenyl)sulfonyl]amino-3(R)-cyclopentoxylbutyric acid (629672-26-0)

Guidance literature:

With palladium 10% on activated carbon; In methanol ethyl acetate;

upstream raw materials:

benzyl 2(R)-amino-3(R)-cyclopentoxylbutyrate trifluoroacetate

Downstream raw materials:

2(R)-[(4-Fluoro-3-methylphenyl)sulfonyl]amino-3(R)-cyclopentoxylbutyric acid

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