methyl p-tolyl 4,7,8,9-tetra-O-acetyl-5-(N-acetylacetamido)-3,5-dideoxy-2-thio-D-glycero-α-D-galacto-2-nonulopyranosonate

Base Information

Chemical Name:methyl p-tolyl 4,7,8,9-tetra-O-acetyl-5-(N-acetylacetamido)-3,5-dideoxy-2-thio-D-glycero-α-D-galacto-2-nonulopyranosonate
CAS No.:374573-38-3
Molecular Formula:C₂₉H₃₇NO₁₃S
Molecular Weight:639.678
Hs Code.:

Synonyms:methyl p-tolyl 4,7,8,9-tetra-O-acetyl-5-(N-acetylacetamido)-3,5-dideoxy-2-thio-D-glycero-α-D-galacto-2-nonulopyranosonate

Suppliers and Price of methyl p-tolyl 4,7,8,9-tetra-O-acetyl-5-(N-acetylacetamido)-3,5-dideoxy-2-thio-D-glycero-α-D-galacto-2-nonulopyranosonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl p-tolyl 4,7,8,9-tetra-O-acetyl-5-(N-acetylacetamido)-3,5-dideoxy-2-thio-D-glycero-α-D-galacto-2-nonulopyranosonate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl p-tolyl 4,7,8,9-tetra-O-acetyl-5-(N-acetylacetamido)-3,5-dideoxy-2-thio-D-glycero-α-D-galacto-2-nonulopyranosonate

There total 4 articles about methyl p-tolyl 4,7,8,9-tetra-O-acetyl-5-(N-acetylacetamido)-3,5-dideoxy-2-thio-D-glycero-α-D-galacto-2-nonulopyranosonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 108-22-5
Isopropenyl acetate

: 167084-05-1
methyl S-4-methylphenyl 5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-2-thio-D-glycero-α-D-galacto-2-nonulopyranosidonate

: 374573-38-3
methyl p-tolyl 4,7,8,9-tetra-O-acetyl-5-(N-acetylacetamido)-3,5-dideoxy-2-thio-D-glycero-α-D-galacto-2-nonulopyranosonate

Guidance literature:: With toluene-4-sulfonic acid; at 60 ℃; for 15h;
DOI:10.1002/1521-3773(20010803)40:15<2900::AID-ANIE2900>3.0.CO;2-4

Reference yield:

: 67670-69-3
N-acetyl-4,7,8,9-tetra-O-acetyl-2-chloro-2-deoxyneuraminic acid methyl ester

: 374573-38-3
methyl p-tolyl 4,7,8,9-tetra-O-acetyl-5-(N-acetylacetamido)-3,5-dideoxy-2-thio-D-glycero-α-D-galacto-2-nonulopyranosonate

Guidance literature:: Multi-step reaction with 2 steps

1: 85 percent / DIPEA / CH₂Cl₂ / 18 h / 20 °C

2: 95 percent / TsOH / 15 h / 60 °C

With toluene-4-sulfonic acid; N-ethyl-N,N-diisopropylamine; In dichloromethane;
DOI:10.1002/1521-3773(20010803)40:15<2900::AID-ANIE2900>3.0.CO;2-4

Reference yield:

: 106-45-6
para-thiocresol

: 374573-38-3
methyl p-tolyl 4,7,8,9-tetra-O-acetyl-5-(N-acetylacetamido)-3,5-dideoxy-2-thio-D-glycero-α-D-galacto-2-nonulopyranosonate

Guidance literature:: Multi-step reaction with 2 steps

1: 85 percent / DIPEA / CH₂Cl₂ / 18 h / 20 °C

2: 95 percent / TsOH / 15 h / 60 °C

With toluene-4-sulfonic acid; N-ethyl-N,N-diisopropylamine; In dichloromethane;
DOI:10.1002/1521-3773(20010803)40:15<2900::AID-ANIE2900>3.0.CO;2-4