C₄₂H₅₂O₈

Base Information

Chemical Name:C₄₂H₅₂O₈
CAS No.:938455-21-1
Molecular Formula:C₄₂H₅₂O₈
Molecular Weight:684.87
Hs Code.:

C<sub>42</sub>H<sub>52</sub>O<sub>8</sub>

Synonyms:C₄₂H₅₂O₈

Suppliers and Price of C₄₂H₅₂O₈

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of C₄₂H₅₂O₈

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of C₄₂H₅₂O₈

There total 42 articles about C₄₂H₅₂O₈ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 938456-10-1
C₂₁H₃₄O₈(C₇H₆)4OCH₂

: 938455-21-1
C₄₂H₅₂O₈

Guidance literature:: With triethylsilane; boron trifluoride diethyl etherate; In acetonitrile; at 0 ℃;
DOI:10.1002/anie.200604625

Reference yield:

: 938455-96-0
C₂₅H₃₂O₅

: 938455-21-1
C₄₂H₅₂O₈

Guidance literature:: Multi-step reaction with 29 steps

1.1: NaH / dimethylformamide / 1.5 h / 0 °C

1.2: Bu₄NI / dimethylformamide / 15 h / 20 °C

2.1: 3.95 g / p-TsOH*H₂O / methanol / 3 h / 40 - 70 °C

3.1: 2,6-lutidine / CH₂Cl₂ / 1.5 h / 20 °C

4.1: 4.77 g / CSA / CH₂Cl₂; methanol / 2 h / 0 °C

5.1: 94 percent / Et₃N; SO₃*pyridine / CH₂Cl₂; dimethylsulfoxide / 2.5 h / 20 °C / Parikh-Doering oxidation

6.1: t-BuLi; HMPA / tetrahydrofuran; pentane / 0.33 h / -78 °C

6.2: 95 percent / tetrahydrofuran; pentane / 1.5 h / -78 °C

7.1: 93 percent / (COCl)2; DMSO; Et₃N / CH₂Cl₂ / -78 - 20 °C

8.1: 98 percent / methanol; tetrahydrofuran / 11 h / 20 °C

9.1: 93 percent / HF*pyridine; pyridine / tetrahydrofuran / 15 h / 20 °C

10.1: 87 percent / pyridinium p-toluenesulfonate / toluene / 3.5 h / 100 °C

11.1: 92 percent / DIBALH / toluene / 2 h / -78 °C

12.1: BH₃*THF / tetrahydrofuran / 3 h / 0 - 20 °C

12.2: 91 percent / aq. NaOH; H₂O₂ / tetrahydrofuran / 3.5 h / 20 °C

13.1: 5.13 g / 2,6-lutidine / CH₂Cl₂ / 1.5 h / 20 °C

14.1: DDQ; phosphate buffer / CH₂Cl₂ / 1 h / 0 °C / pH 7

15.1: tetra-n-propylammonium perruthenate; NMO; molecular sieves 4 Angstroem / CH₂Cl₂ / 6.08 h / 0 - 20 °C

16.1: 2.89 g / TBAF; acetic acid / tetrahydrofuran / 7.5 h / 20 °C

17.1: 83 percent / TMSOTf; Et₃SiH / acetonitrile / 0.25 h / -10 °C

18.1: 3.14 g / 2,6-lutidine / CH₂Cl₂ / 2.5 h / 20 °C

19.1: H₂ / Pd/C / methanol / 17 h / 20 °C

20.1: CSA / dimethylformamide / 6.5 h / 30 °C

20.2: 1.09 g / pyridinium p-toluenesulfonate / CH₂Cl₂; methanol / 1 h / 0 °C

21.1: 85 percent / pyridine / 0.67 h / 0 °C

22.1: NaH / dimethylformamide / 1 h / 0 °C

22.2: 0.22 g / Bu₄NI / dimethylformamide / 6 h / 20 °C

23.1: 72 percent / DIBALH / CH₂Cl₂; hexane / 0.5 h / -78 °C

24.1: Bu₃P / tetrahydrofuran / 0.75 h / 20 °C

25.1: 0.11 g / m-CPBA / CH₂Cl₂ / 0.75 h / 0 °C

26.1: 92 percent / TBAF / tetrahydrofuran / 16 h / 20 °C

27.1: p-TsOH*H₂O / methanol / 1 h / 0 °C

28.1: NaH / dimethylformamide / 1 h / 0 °C

28.2: 0.25 g / Bu₄NI / dimethylformamide / 17.5 h / 20 °C

29.1: 0.18 g / Et₃SiH; BF₃*OEt₂ / acetonitrile / 0.75 h / 0 °C

With pyridine; 2,6-dimethylpyridine; triethylsilane; N,N,N,N,N,N-hexamethylphosphoric triamide; N-methyl-2-indolinone; phosphate buffer; tetrapropylammonium perruthennate; borane-THF; oxalyl dichloride; pyridine-SO₃ complex; tributylphosphine; trimethylsilyl trifluoromethanesulfonate; 4 A molecular sieve; camphor-10-sulfonic acid; boron trifluoride diethyl etherate; tetrabutyl ammonium fluoride; hydrogen; tert.-butyl lithium; pyridinium p-toluenesulfonate; sodium hydride; diisobutylaluminium hydride; toluene-4-sulfonic acid; pyridine hydrogenfluoride; acetic acid; dimethyl sulfoxide; triethylamine; 3-chloro-benzenecarboperoxoic acid; 2,3-dicyano-5,6-dichloro-p-benzoquinone; palladium on activated charcoal; In tetrahydrofuran; methanol; hexane; dichloromethane; dimethyl sulfoxide; N,N-dimethyl-formamide; toluene; acetonitrile; pentane; 7.1: Swern oxidation;
DOI:10.1016/j.tet.2007.02.039

Reference yield:

: C₂₅H₃₄O₅(SiC₆H₁₄)2

: 938455-21-1
C₄₂H₅₂O₈

Guidance literature:: Multi-step reaction with 26 steps

1.1: 4.77 g / CSA / CH₂Cl₂; methanol / 2 h / 0 °C

2.1: 94 percent / Et₃N; SO₃*pyridine / CH₂Cl₂; dimethylsulfoxide / 2.5 h / 20 °C / Parikh-Doering oxidation

3.1: t-BuLi; HMPA / tetrahydrofuran; pentane / 0.33 h / -78 °C

3.2: 95 percent / tetrahydrofuran; pentane / 1.5 h / -78 °C

4.1: 93 percent / (COCl)2; DMSO; Et₃N / CH₂Cl₂ / -78 - 20 °C

5.1: 98 percent / methanol; tetrahydrofuran / 11 h / 20 °C

6.1: 93 percent / HF*pyridine; pyridine / tetrahydrofuran / 15 h / 20 °C

7.1: 87 percent / pyridinium p-toluenesulfonate / toluene / 3.5 h / 100 °C

8.1: 92 percent / DIBALH / toluene / 2 h / -78 °C

9.1: BH₃*THF / tetrahydrofuran / 3 h / 0 - 20 °C

9.2: 91 percent / aq. NaOH; H₂O₂ / tetrahydrofuran / 3.5 h / 20 °C

10.1: 5.13 g / 2,6-lutidine / CH₂Cl₂ / 1.5 h / 20 °C

11.1: DDQ; phosphate buffer / CH₂Cl₂ / 1 h / 0 °C / pH 7

12.1: tetra-n-propylammonium perruthenate; NMO; molecular sieves 4 Angstroem / CH₂Cl₂ / 6.08 h / 0 - 20 °C

13.1: 2.89 g / TBAF; acetic acid / tetrahydrofuran / 7.5 h / 20 °C

14.1: 83 percent / TMSOTf; Et₃SiH / acetonitrile / 0.25 h / -10 °C

15.1: 3.14 g / 2,6-lutidine / CH₂Cl₂ / 2.5 h / 20 °C

16.1: H₂ / Pd/C / methanol / 17 h / 20 °C

17.1: CSA / dimethylformamide / 6.5 h / 30 °C

17.2: 1.09 g / pyridinium p-toluenesulfonate / CH₂Cl₂; methanol / 1 h / 0 °C

18.1: 85 percent / pyridine / 0.67 h / 0 °C

19.1: NaH / dimethylformamide / 1 h / 0 °C

19.2: 0.22 g / Bu₄NI / dimethylformamide / 6 h / 20 °C

20.1: 72 percent / DIBALH / CH₂Cl₂; hexane / 0.5 h / -78 °C

21.1: Bu₃P / tetrahydrofuran / 0.75 h / 20 °C

22.1: 0.11 g / m-CPBA / CH₂Cl₂ / 0.75 h / 0 °C

23.1: 92 percent / TBAF / tetrahydrofuran / 16 h / 20 °C

24.1: p-TsOH*H₂O / methanol / 1 h / 0 °C

25.1: NaH / dimethylformamide / 1 h / 0 °C

25.2: 0.25 g / Bu₄NI / dimethylformamide / 17.5 h / 20 °C

26.1: 0.18 g / Et₃SiH; BF₃*OEt₂ / acetonitrile / 0.75 h / 0 °C

With pyridine; 2,6-dimethylpyridine; triethylsilane; N,N,N,N,N,N-hexamethylphosphoric triamide; N-methyl-2-indolinone; phosphate buffer; tetrapropylammonium perruthennate; borane-THF; oxalyl dichloride; pyridine-SO₃ complex; tributylphosphine; trimethylsilyl trifluoromethanesulfonate; 4 A molecular sieve; camphor-10-sulfonic acid; boron trifluoride diethyl etherate; tetrabutyl ammonium fluoride; hydrogen; tert.-butyl lithium; pyridinium p-toluenesulfonate; sodium hydride; diisobutylaluminium hydride; toluene-4-sulfonic acid; pyridine hydrogenfluoride; acetic acid; dimethyl sulfoxide; triethylamine; 3-chloro-benzenecarboperoxoic acid; 2,3-dicyano-5,6-dichloro-p-benzoquinone; palladium on activated charcoal; In tetrahydrofuran; methanol; hexane; dichloromethane; dimethyl sulfoxide; N,N-dimethyl-formamide; toluene; acetonitrile; pentane; 4.1: Swern oxidation;
DOI:10.1016/j.tet.2007.02.039