N-[2-(3-{1-ethyl-4-(phenylethynyl)-5-[4-(trifluoromethyl)phenoxy]-1H-pyrazol-3-yl}phenyl)propan-2-yl]-2,2,2-trifluoroethanesulfonamide

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Chemical Name:N-[2-(3-{1-ethyl-4-(phenylethynyl)-5-[4-(trifluoromethyl)phenoxy]-1H-pyrazol-3-yl}phenyl)propan-2-yl]-2,2,2-trifluoroethanesulfonamide
CAS No.:1289202-94-3
Molecular Formula:C₃₁H₂₇F₆N₃O₃S
Molecular Weight:635.63
Hs Code.:

Synonyms:N-[2-(3-{1-ethyl-4-(phenylethynyl)-5-[4-(trifluoromethyl)phenoxy]-1H-pyrazol-3-yl}phenyl)propan-2-yl]-2,2,2-trifluoroethanesulfonamide

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Chemical Property of N-[2-(3-{1-ethyl-4-(phenylethynyl)-5-[4-(trifluoromethyl)phenoxy]-1H-pyrazol-3-yl}phenyl)propan-2-yl]-2,2,2-trifluoroethanesulfonamide

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Technology Process of N-[2-(3-{1-ethyl-4-(phenylethynyl)-5-[4-(trifluoromethyl)phenoxy]-1H-pyrazol-3-yl}phenyl)propan-2-yl]-2,2,2-trifluoroethanesulfonamide

There total 2 articles about N-[2-(3-{1-ethyl-4-(phenylethynyl)-5-[4-(trifluoromethyl)phenoxy]-1H-pyrazol-3-yl}phenyl)propan-2-yl]-2,2,2-trifluoroethanesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 66582-10-3
(3 -phenylprop-1-yn-1-yl)copper

: 1289202-91-0
N-[2-(3-{1-ethyl-4-iodo-5-[4-(trifluoromethyl)phenoxy]-1H-pyrazol-3-yl}phenyl)propan-2-yl]-2,2,2-trifluoroethanesulfonamide

: 1289202-94-3
N-[2-(3-{1-ethyl-4-(phenylethynyl)-5-[4-(trifluoromethyl)phenoxy]-1H-pyrazol-3-yl}phenyl)propan-2-yl]-2,2,2-trifluoroethanesulfonamide

Guidance literature:: With pyridine; at 100 ℃; for 48h; Inert atmosphere; Microwave irradiation; Sealed tube;

Reference yield:

: 1289201-82-6
N-[1-(3-{1-ethyl-3-[4-(trifluoromethyl)phenoxy]-1H-pyrazol-5-yl}phenyl)-1-methylethyl]-2,2,2-trifluoroethanesulfonamide

: 1289202-94-3
N-[2-(3-{1-ethyl-4-(phenylethynyl)-5-[4-(trifluoromethyl)phenoxy]-1H-pyrazol-3-yl}phenyl)propan-2-yl]-2,2,2-trifluoroethanesulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1: N-iodo-succinimide / dichloromethane / 0 °C

2: pyridine / 48 h / 100 °C / Inert atmosphere; Microwave irradiation; Sealed tube

With pyridine; N-iodo-succinimide; In dichloromethane;