o-mesyloxyphenacyl bromide

Base Information

• Chemical Name: o-mesyloxyphenacyl bromide
• CAS No.: 332841-50-6
• Molecular Formula: C₉H₉BrO₄S
• Molecular Weight: 293.138
• Mol file: 332841-50-6.mol

Synonyms:o-mesyloxyphenacyl bromide

Chemical Property of o-mesyloxyphenacyl bromide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of o-mesyloxyphenacyl bromide

There total 4 articles about o-mesyloxyphenacyl bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

2-acetylphenyl methanesulfonate (99179-74-5) → o-mesyloxyphenacyl bromide (332841-50-6)

Guidance literature:

With benzyltrimethylammonium tribromide; In dichloromethane;

DOI:10.1016/S0040-4039(00)02222-X

Reference yield:

2-methanesulfonyloxy-1-ethylbenzene → 2-acetylphenyl methanesulfonate (99179-74-5) + o-mesyloxyphenacyl bromide (332841-50-6)

Guidance literature:

With N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); water; In acetonitrile; at 80 ℃; for 8h;

DOI:10.1021/acs.orglett.6b00048

Reference yield:

2-methanesulfonyloxy-1-ethylbenzene → o-mesyloxyphenacyl bromide (332841-50-6)

Guidance literature:

With N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); water; In acetonitrile; at 80 ℃; for 12h;

DOI:10.1002/ejoc.201900100

upstream raw materials:

2-acetylphenyl methanesulfonate

o-hydroxyacetophenone

Downstream raw materials:

methanesulfonic acid 2-[1-(3,4-dimethoxy-phenyl)-8,9-dimethoxy-5,6-dihydro-pyrrolo[2,1-a]isoquinolin-2-yl]-phenyl ester

methanesulfonic acid 2-[1-(3,4-dimethoxy-phenyl)-3-formyl-8,9-dimethoxy-5,6-dihydro-pyrrolo[2,1-a]isoquinolin-2-yl]-phenyl ester

1-(3,4-dimethoxy-phenyl)-2-(2-hydroxy-phenyl)-8,9-dimethoxy-5,6-dihydro-pyrrolo[2,1-a]isoquinoline-3-carbaldehyde