N⁵,N^5'-Bis-[1-phenyl-meth-(E)-ylidene]-[2,2']bipyridinyl-5,5'-diamine

Base Information

• Chemical Name: N⁵,N^5'-Bis-[1-phenyl-meth-(E)-ylidene]-[2,2']bipyridinyl-5,5'-diamine
• CAS No.: 187461-62-7
• Molecular Formula: C₂₄H₁₈N₄
• Molecular Weight: 362.434
• Mol file: 187461-62-7.mol

Synonyms:N⁵,N^5'-Bis-[1-phenyl-meth-(E)-ylidene]-[2,2']bipyridinyl-5,5'-diamine

Chemical Property of N⁵,N^5'-Bis-[1-phenyl-meth-(E)-ylidene]-[2,2']bipyridinyl-5,5'-diamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N⁵,N^5'-Bis-[1-phenyl-meth-(E)-ylidene]-[2,2']bipyridinyl-5,5'-diamine

There total 3 articles about N⁵,N^5'-Bis-[1-phenyl-meth-(E)-ylidene]-[2,2']bipyridinyl-5,5'-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-benzylidene-5-amino-2-chloropyridine (5325-71-3) → N5,N5'-Bis-[1-phenyl-meth-(E)-ylidene]-[2,2']bipyridinyl-5,5'-diamine (187461-62-7)

Guidance literature:

With dibromobis(triphenylphosphine)nickel(II); tetraethylammonium iodide; zinc; In tetrahydrofuran; at 50 - 80 ℃; for 20h;

DOI:10.1021/ja963769d

Reference yield:

6-Chloro-pyridin-3-ylamine (5350-93-6) → N5,N5'-Bis-[1-phenyl-meth-(E)-ylidene]-[2,2']bipyridinyl-5,5'-diamine (187461-62-7)

Guidance literature:

Multi-step reaction with 2 steps

1: MgSO₄, triethylamine / CH₂Cl₂ / 24 h / Ambient temperature

2: NiBr₂(PPh₃)2, Zn, Et₄NI / tetrahydrofuran / 20 h / 50 - 80 °C

With dibromobis(triphenylphosphine)nickel(II); tetraethylammonium iodide; magnesium sulfate; triethylamine; zinc; In tetrahydrofuran; dichloromethane;

DOI:10.1021/ja963769d

Reference yield:

2-chloro-5-nitropyridine (4548-45-2) → N5,N5'-Bis-[1-phenyl-meth-(E)-ylidene]-[2,2']bipyridinyl-5,5'-diamine (187461-62-7)

Guidance literature:

Multi-step reaction with 3 steps

1: iron, ammonium chloride / H₂O; methanol / Ambient temperature

2: MgSO₄, triethylamine / CH₂Cl₂ / 24 h / Ambient temperature

3: NiBr₂(PPh₃)2, Zn, Et₄NI / tetrahydrofuran / 20 h / 50 - 80 °C

With dibromobis(triphenylphosphine)nickel(II); ammonium chloride; tetraethylammonium iodide; iron; magnesium sulfate; triethylamine; zinc; In tetrahydrofuran; methanol; dichloromethane; water;

DOI:10.1021/ja963769d

upstream raw materials:

N-benzylidene-5-amino-2-chloropyridine

6-Chloro-pyridin-3-ylamine

2-chloro-5-nitropyridine