(2-oxo-1-phenylthiocarbamoylpropyl)phosphonic acid diethyl ester

Base Information

• Chemical Name: (2-oxo-1-phenylthiocarbamoylpropyl)phosphonic acid diethyl ester
• CAS No.: 1347761-81-2
• Molecular Formula: C₁₄H₂₀NO₄PS
• Molecular Weight: 329.357
• Mol file: 1347761-81-2.mol

Synonyms:(2-oxo-1-phenylthiocarbamoylpropyl)phosphonic acid diethyl ester

Chemical Property of (2-oxo-1-phenylthiocarbamoylpropyl)phosphonic acid diethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of (2-oxo-1-phenylthiocarbamoylpropyl)phosphonic acid diethyl ester

There total 1 articles about (2-oxo-1-phenylthiocarbamoylpropyl)phosphonic acid diethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

Diethyl (2-oxopropyl)phosphonate (1067-71-6) + phenyl isothiocyanate (103-72-0) → (2-oxo-1-phenylthiocarbamoylpropyl)phosphonic acid diethyl ester (1347761-81-2)

Guidance literature:

Diethyl (2-oxopropyl)phosphonate; With potassium tert-butylate; In tetrahydrofuran; at 20 ℃; for 2h; Inert atmosphere;

phenyl isothiocyanate; In tetrahydrofuran; at 20 ℃; for 16h; Inert atmosphere;

With water; ammonium chloride; In tetrahydrofuran; Inert atmosphere; Saturated solution;

DOI:10.1016/j.tet.2011.09.093

Reference yield: 76.0%

(2-oxo-1-phenylthiocarbamoylpropyl)phosphonic acid diethyl ester (1347761-81-2) → phenylthiocarbamoylmethylphosphonic acid diethyl ester (1347761-86-7)

Guidance literature:

With unsubstituted or substituted hydrazine; In ethanol; at 20 ℃; for 24h;

DOI:10.1016/j.tet.2011.09.093

upstream raw materials:

Diethyl (2-oxopropyl)phosphonate

phenyl isothiocyanate

Downstream raw materials:

phenylthiocarbamoylmethylphosphonic acid diethyl ester