5-HYDROXYBENZOFURAZAN

Base Information

• Chemical Name: 5-HYDROXYBENZOFURAZAN
• CAS No.: 768-09-2
• Molecular Formula: C₆H₄N₂O₂
• Molecular Weight: 136.11
• Hs Code.: 2934999090
• Mol file: 768-09-2.mol

Synonyms:5-Benzofurazanol(7CI,8CI);5-Hydroxy-2,1,3-benzoxadiazole;5-Hydroxybenzofurazan;5-Hydroxy-2,1,3-benzoxadiazole;5-Hydroxybenzofurazan;

Chemical Property of 5-HYDROXYBENZOFURAZAN

Chemical Property:

• Vapor Pressure: 0.003mmHg at 25°C
• Melting Point: 103 °C
• Refractive Index: 1.68
• Boiling Point: 278.218 °C at 760 mmHg
• PKA: 7.28±0.40(Predicted)
• Flash Point: 122.062 °C
• PSA: 59.15000
• Density: 1.492 g/cm³
• LogP: 0.92840

Purity/Quality:

99% ^*data from raw suppliers

5-Hydroxybenzofurazan ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi,Xn
• Statements: 36/37/38-22
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 5-Hydroxybenzofurazan is a potential scaffold to develop drugs for cancer.

Technology Process of 5-HYDROXYBENZOFURAZAN

There total 1 articles about 5-HYDROXYBENZOFURAZAN which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ benzo[2,1,3]oxadiazol-5-ol (768-09-2)

Guidance literature:

entspr.Methoxyverb.,HBr;

Reference yield:

benzo[2,1,3]oxadiazol-5-ol (768-09-2) + N,N′-1,3-bis(2,6-diisopropylphenyl)-2-chloroimidazolium chloride (1228185-09-8) → C33H39N4O2(1+)*Cl(1-)

Guidance literature:

With silver carbonate; In chloroform; at 60 ℃;

DOI:10.1038/nature17667

Reference yield:

benzo[2,1,3]oxadiazol-5-ol (768-09-2) + N,N′-1,3-bis(2,6-diisopropylphenyl)-2-chloroimidazolium chloride (1228185-09-8) → C33H39(18)FN4O2

Guidance literature:

Multi-step reaction with 2 steps

1: silver carbonate / chloroform / 60 °C

2: ¹⁸F-fluoride anion exchange cartridge / butanone; ethanol

With silver carbonate; In ethanol; chloroform; butanone;

DOI:10.1038/nature17667