1-((4-Fluorophenyl)(phenyl)methyl)piperazine

Base Information

Chemical Name:1-((4-Fluorophenyl)(phenyl)methyl)piperazine
CAS No.:27064-89-7
Molecular Formula:C17H19 F N2
Molecular Weight:270.35
Hs Code.:2933599090
European Community (EC) Number:671-608-7
DSSTox Substance ID:DTXSID00381225
Mol file:27064-89-7.mol

Synonyms:27064-89-7;1-((4-fluorophenyl)(phenyl)methyl)piperazine;1-[(4-fluorophenyl)(phenyl)methyl]piperazine;1-(4-fluoro-alpha-phenylbenzyl)piperazine;1-[(4-fluorophenyl)-phenylmethyl]piperazine;[(4-fluorophenyl)phenylmethyl]piperazine;1-(4-fluorobenzhydryl)piperazine;1-(4-fluorophenylmethyl)piperazine;1-[(4-fluorophenyl)-phenyl-methyl]piperazine;4-fluorobenzhydrylpiperazine;SCHEMBL1138318;DTXSID00381225;KKMSCNTZDCYNSC-UHFFFAOYSA-N;AR3887;BBL020678;MFCD00426601;STK893368;AKOS001476125;1-(4-Fluoro-A-phenylbenzyl)piperazine;AS-45706;1-[(4-fluorophenyl)phenylmethyl]piperazine;1-(4-Fluoro- alpha -phenylbenzyl)piperazine;CS-0171264;FT-0638666;Piperazine,1-[(4-fluorophenyl)phenylmethyl]-;EN300-3316261;A818897;(+/-)-1-[(4-Fluorophenyl)phenylmethyl]piperazine

Suppliers and Price of 1-((4-Fluorophenyl)(phenyl)methyl)piperazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
1-[(4-Fluorophenyl)(phenyl)methyl]piperazine
1 g
$ 295.00

SynQuest Laboratories
1-[(4-Fluorophenyl)(phenyl)methyl]piperazine
250 mg
$ 200.00

Matrix Scientific
1-(4-Fluoro-alpha-phenylbenzyl)piperazine 98%
500mg
$ 51.00

Crysdot
1-((4-Fluorophenyl)(phenyl)methyl)piperazine 95+%
10g
$ 587.00

Crysdot
1-((4-Fluorophenyl)(phenyl)methyl)piperazine 95+%
5g
$ 309.00

Crysdot
1-((4-Fluorophenyl)(phenyl)methyl)piperazine 95+%
25g
$ 1084.00

AstaTech
[(4-FLUOROPHENYL)PHENYLMETHYL]PIPERAZINE 95%
25 / G
$ 1382.00

AstaTech
[(4-FLUOROPHENYL)PHENYLMETHYL]PIPERAZINE 95%
1 / G
$ 132.00

AstaTech
[(4-FLUOROPHENYL)PHENYLMETHYL]PIPERAZINE 95%
5 / G
$ 395.00

Apolloscientific
1-(4-Fluorobenzhydryl)piperazine
5g
$ 450.00

Total 12 raw suppliers

Chemical Property of 1-((4-Fluorophenyl)(phenyl)methyl)piperazine

Chemical Property:

Vapor Pressure:1.43E-05mmHg at 25°C
Melting Point:82-84°C
Boiling Point:366.7°Cat760mmHg
PKA:9.01±0.10(Predicted)
Flash Point:175.6°C
PSA：15.27000
Density:1.126g/cm³
LogP:3.08700
XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:270.15322678
Heavy Atom Count:20
Complexity:277

Purity/Quality:

97% ^*data from raw suppliers

1-[(4-Fluorophenyl)(phenyl)methyl]piperazine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36/37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCN1)C(C2=CC=CC=C2)C3=CC=C(C=C3)F

Technology Process of 1-((4-Fluorophenyl)(phenyl)methyl)piperazine

There total 6 articles about 1-((4-Fluorophenyl)(phenyl)methyl)piperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

: 110-85-0
piperazine

: 365-21-9
1-(chlorophenylmethyl)-4-fluorobenzene

: 27064-89-7
(+)-1-[(4-fluorophenyl)phenylmethyl)piperazine

Guidance literature:: In toluene; at 100 ℃;
DOI:10.1016/j.bioorg.2019.103217

Reference yield:

: 149099-27-4,149243-88-9,365-22-0
4-fluorobenzhydrol

: 27064-89-7
(+)-1-[(4-fluorophenyl)phenylmethyl)piperazine

Guidance literature:: Multi-step reaction with 2 steps

1: thionyl chloride / dichloromethane / 20 °C / Reflux

2: potassium iodide; potassium carbonate / acetonitrile / Reflux

With thionyl chloride; potassium carbonate; potassium iodide; In dichloromethane; acetonitrile;

Reference yield:

: 345-83-5
4-fluorobenzophenone

: 27064-89-7
(+)-1-[(4-fluorophenyl)phenylmethyl)piperazine

Guidance literature:: Multi-step reaction with 3 steps

1: sodium tetrahydroborate / methanol

2: thionyl chloride / dichloromethane / 20 °C

3: N,N-dimethyl-formamide / 80 °C

With sodium tetrahydroborate; thionyl chloride; In methanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1155/2016/4617454