(2S,3R)-N₁-(5-chloro-1,3-benzoxazol-2-yl)-3-(4-methoxyphenyl)-2-(pyridin-2-yl)-1-pyrrolidinecarbothioamide

Base Information

• Chemical Name: (2S,3R)-N₁-(5-chloro-1,3-benzoxazol-2-yl)-3-(4-methoxyphenyl)-2-(pyridin-2-yl)-1-pyrrolidinecarbothioamide
• CAS No.: 1098300-19-6
• Molecular Formula: C₂₄H₂₁ClN₄O₂S
• Molecular Weight: 464.975

Synonyms:(2S,3R)-N₁-(5-chloro-1,3-benzoxazol-2-yl)-3-(4-methoxyphenyl)-2-(pyridin-2-yl)-1-pyrrolidinecarbothioamide

Chemical Property of (2S,3R)-N₁-(5-chloro-1,3-benzoxazol-2-yl)-3-(4-methoxyphenyl)-2-(pyridin-2-yl)-1-pyrrolidinecarbothioamide

Chemical Property:

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Technology Process of (2S,3R)-N₁-(5-chloro-1,3-benzoxazol-2-yl)-3-(4-methoxyphenyl)-2-(pyridin-2-yl)-1-pyrrolidinecarbothioamide

There total 1 articles about (2S,3R)-N₁-(5-chloro-1,3-benzoxazol-2-yl)-3-(4-methoxyphenyl)-2-(pyridin-2-yl)-1-pyrrolidinecarbothioamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(2S,3R)-2-(pyridin-2-yl)-3-(4-methoxyphenyl)pyrrolidine (187934-90-3) + 2-hydroxy-5-chloro-aniline (95-85-2) → (2S,3R)-N1-(5-chloro-1,3-benzoxazol-2-yl)-3-(4-methoxyphenyl)-2-(pyridin-2-yl)-1-pyrrolidinecarbothioamide (1098300-19-6)

Guidance literature:

With carbon disulfide; dihydrogen peroxide; triethylamine; In tetrahydrofuran;

upstream raw materials:

(2S,3R)-2-(pyridin-2-yl)-3-(4-methoxyphenyl)pyrrolidine

2-hydroxy-5-chloro-aniline

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