N₁-[(3R,7S)-1-isobutyl-2-oxo-7-phenyl-2,3,4,7-tetrahydro-1H-azepin-3-yl]-N₂-[(3,5-difluorophenyl)acetyl]-L-alaninamide

Base Information

• Chemical Name: N₁-[(3R,7S)-1-isobutyl-2-oxo-7-phenyl-2,3,4,7-tetrahydro-1H-azepin-3-yl]-N₂-[(3,5-difluorophenyl)acetyl]-L-alaninamide
• CAS No.: 762289-69-0
• Molecular Formula: C₂₇H₃₁F₂N₃O₃
• Molecular Weight: 483.558

Synonyms:N₁-[(3R,7S)-1-isobutyl-2-oxo-7-phenyl-2,3,4,7-tetrahydro-1H-azepin-3-yl]-N₂-[(3,5-difluorophenyl)acetyl]-L-alaninamide

Chemical Property of N₁-[(3R,7S)-1-isobutyl-2-oxo-7-phenyl-2,3,4,7-tetrahydro-1H-azepin-3-yl]-N₂-[(3,5-difluorophenyl)acetyl]-L-alaninamide

Chemical Property:

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Technology Process of N₁-[(3R,7S)-1-isobutyl-2-oxo-7-phenyl-2,3,4,7-tetrahydro-1H-azepin-3-yl]-N₂-[(3,5-difluorophenyl)acetyl]-L-alaninamide

There total 1 articles about N₁-[(3R,7S)-1-isobutyl-2-oxo-7-phenyl-2,3,4,7-tetrahydro-1H-azepin-3-yl]-N₂-[(3,5-difluorophenyl)acetyl]-L-alaninamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

C16H22N2O (762289-73-6) + N-(3,5-Difluorophenylacetyl)-L-alanine (208124-34-9) → N1-[(3S,7S)-1-isobutyl-2-oxo-7-phenyl-2,3,4,7-tetrahydro-1H-azepin-3-yl]-N2-[(3,5-difluorophenyl)acetyl]-L-alaninamide + N1-[(3R,7S)-1-isobutyl-2-oxo-7-phenyl-2,3,4,7-tetrahydro-1H-azepin-3-yl]-N2-[(3,5-difluorophenyl)acetyl]-L-alaninamide (762289-69-0)

Guidance literature:

With 4-methyl-morpholine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 0 - 20 ℃;

upstream raw materials:

C₁₆H₂₂N₂O

N-(3,5-Difluorophenylacetyl)-L-alanine

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