estradiol-17β-O-4-oxobutanoyl-Arg(Nω-NO2)-Gly-Asp(OBn)-Val-Arg(Nω-NO2)-Gly-Asp(OBn)-Val-OBn

Base Information

Chemical Name:estradiol-17β-O-4-oxobutanoyl-Arg(Nω-NO2)-Gly-Asp(OBn)-Val-Arg(Nω-NO2)-Gly-Asp(OBn)-Val-OBn
CAS No.:1147834-81-8
Molecular Formula:C₇₇H₁₀₂N₁₆O₂₁
Molecular Weight:1587.75
Hs Code.:

Synonyms:estradiol-17β-O-4-oxobutanoyl-Arg(Nω-NO2)-Gly-Asp(OBn)-Val-Arg(Nω-NO2)-Gly-Asp(OBn)-Val-OBn

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Chemical Property of estradiol-17β-O-4-oxobutanoyl-Arg(Nω-NO2)-Gly-Asp(OBn)-Val-Arg(Nω-NO2)-Gly-Asp(OBn)-Val-OBn

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Technology Process of estradiol-17β-O-4-oxobutanoyl-Arg(Nω-NO2)-Gly-Asp(OBn)-Val-Arg(Nω-NO2)-Gly-Asp(OBn)-Val-OBn

There total 1 articles about estradiol-17β-O-4-oxobutanoyl-Arg(Nω-NO2)-Gly-Asp(OBn)-Val-Arg(Nω-NO2)-Gly-Asp(OBn)-Val-OBn which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.4%

: 1147834-47-6
Arg(Nω-NO2)-Gly-Asp(OBn)-Val-Arg(Nω-NO2)-Gly-Asp(OBn)-Val-OBn hydrochloride

: 7698-93-3
Estradiol-17-hemisuccinate

: 1147834-81-8
estradiol-17β-O-4-oxobutanoyl-Arg(Nω-NO2)-Gly-Asp(OBn)-Val-Arg(Nω-NO2)-Gly-Asp(OBn)-Val-OBn

Guidance literature:: Estradiol-17-hemisuccinate; With benzotriazol-1-ol; dicyclohexyl-carbodiimide; In tetrahydrofuran; at 0 ℃; for 0.5h; under 750.075 Torr; Inert atmosphere;

Arg(Nω-NO2)-Gly-Asp(OBn)-Val-Arg(Nω-NO2)-Gly-Asp(OBn)-Val-OBn hydrochloride; With 4-methyl-morpholine; In tetrahydrofuran; at 0 ℃; under 750.075 Torr; pH=8.5; Inert atmosphere;
DOI:10.1016/j.ejmech.2008.09.036