4-(3-{[4-chloro-6-(methylsulfonyl)-1-oxypyridin-2-yl]oxy}phenyl)-3-methyl-8-(trifluoromethyl)quinoline

Base Information

Chemical Name:4-(3-{[4-chloro-6-(methylsulfonyl)-1-oxypyridin-2-yl]oxy}phenyl)-3-methyl-8-(trifluoromethyl)quinoline
CAS No.:1020736-48-4
Molecular Formula:C₂₃H₁₆ClF₃N₂O₄S
Molecular Weight:508.905
Hs Code.:

Synonyms:4-(3-{[4-chloro-6-(methylsulfonyl)-1-oxypyridin-2-yl]oxy}phenyl)-3-methyl-8-(trifluoromethyl)quinoline

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Chemical Property of 4-(3-{[4-chloro-6-(methylsulfonyl)-1-oxypyridin-2-yl]oxy}phenyl)-3-methyl-8-(trifluoromethyl)quinoline

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Technology Process of 4-(3-{[4-chloro-6-(methylsulfonyl)-1-oxypyridin-2-yl]oxy}phenyl)-3-methyl-8-(trifluoromethyl)quinoline

There total 1 articles about 4-(3-{[4-chloro-6-(methylsulfonyl)-1-oxypyridin-2-yl]oxy}phenyl)-3-methyl-8-(trifluoromethyl)quinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

: 1020736-47-3
4-[3-(4,6-dichloro-1-oxy-pyridin-2-yloxy)-phenyl]-3-methyl-8-trifluoromethyl-quinoline

: 20277-69-4
sodium methansulfinate

: 1020736-48-4
4-(3-{[4-chloro-6-(methylsulfonyl)-1-oxypyridin-2-yl]oxy}phenyl)-3-methyl-8-(trifluoromethyl)quinoline

Guidance literature:: In N,N-dimethyl-formamide; at 80 ℃;

Reference yield: 64.0%

: 1020736-48-4
4-(3-{[4-chloro-6-(methylsulfonyl)-1-oxypyridin-2-yl]oxy}phenyl)-3-methyl-8-(trifluoromethyl)quinoline

: 1020736-49-5
4-[3-(4-chloro-6-methanesulfonyl-pyridin-2-yloxy)-phenyl]-3-methyl-8-trifluoromethyl-quinoline

Guidance literature:: 4-(3-{[4-chloro-6-(methylsulfonyl)-1-oxypyridin-2-yl]oxy}phenyl)-3-methyl-8-(trifluoromethyl)quinoline; With phosphorus tribromide; In dichloromethane;

With water; sodium hydrogencarbonate; In dichloromethane;