N,N',N''-trioctadecyl-3,3',3''-[(4-methoxycarbonylphenyl-carbonylamino)methanetriyl]tripropanamide

Base Information

• Chemical Name: N,N',N''-trioctadecyl-3,3',3''-[(4-methoxycarbonylphenyl-carbonylamino)methanetriyl]tripropanamide
• CAS No.: 926649-25-4
• Molecular Formula: C₇₃H₁₃₄N₄O₆
• Molecular Weight: 1163.89
• Mol file: 926649-25-4.mol

Synonyms:N,N',N''-trioctadecyl-3,3',3''-[(4-methoxycarbonylphenyl-carbonylamino)methanetriyl]tripropanamide

Chemical Property of N,N',N''-trioctadecyl-3,3',3''-[(4-methoxycarbonylphenyl-carbonylamino)methanetriyl]tripropanamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N,N',N''-trioctadecyl-3,3',3''-[(4-methoxycarbonylphenyl-carbonylamino)methanetriyl]tripropanamide

There total 4 articles about N,N',N''-trioctadecyl-3,3',3''-[(4-methoxycarbonylphenyl-carbonylamino)methanetriyl]tripropanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

N,N',N''-trioctadecyl-3,3',3''-(1-aminomethanetriyl)tripropanamide (926649-22-1) + Monomethyl terephthalate (1679-64-7) → N,N',N''-trioctadecyl-3,3',3''-[(4-methoxycarbonylphenyl-carbonylamino)methanetriyl]tripropanamide (926649-25-4)

Guidance literature:

Monomethyl terephthalate; With thionyl chloride; N,N-dimethyl-formamide; Heating;

N,N',N''-trioctadecyl-3,3',3''-(1-aminomethanetriyl)tripropanamide; With triethylamine; In tetrahydrofuran; at 40 ℃; Further stages.;

DOI:10.1039/b609645j

Reference yield:

N,N',N''-trioctadecyl-3,3',3''-(1-nitromethanetriyl)tripropanamide (926649-20-9) → N,N',N''-trioctadecyl-3,3',3''-[(4-methoxycarbonylphenyl-carbonylamino)methanetriyl]tripropanamide (926649-25-4)

Guidance literature:

Multi-step reaction with 2 steps

1.1: 77 percent / H₂ / Raney-Ni / ethanol / 24 h / 60 °C / 2625.26 Torr

2.1: SOCl₂; DMF / Heating

2.2: 75 percent / Et₃N / tetrahydrofuran / 40 °C

With thionyl chloride; hydrogen; N,N-dimethyl-formamide; nickel; In ethanol;

DOI:10.1039/b609645j

Reference yield:

4-(2-carboxyethyl)-4-nitroheptanedioic acid (59085-15-3) → N,N',N''-trioctadecyl-3,3',3''-[(4-methoxycarbonylphenyl-carbonylamino)methanetriyl]tripropanamide (926649-25-4)

Guidance literature:

Multi-step reaction with 3 steps

1.1: SOCl; DMF / Heating

1.2: 50 percent / Et₃N / tetrahydrofuran / 96 h / 40 °C

2.1: 77 percent / H₂ / Raney-Ni / ethanol / 24 h / 60 °C / 2625.26 Torr

3.1: SOCl₂; DMF / Heating

3.2: 75 percent / Et₃N / tetrahydrofuran / 40 °C

With thionyl chloride; hydrogen; N,N-dimethyl-formamide; nickel; In ethanol;

DOI:10.1039/b609645j

upstream raw materials:

N,N',N''-trioctadecyl-3,3',3''-(1-aminomethanetriyl)tripropanamide

Monomethyl terephthalate

N,N',N''-trioctadecyl-3,3',3''-(1-nitromethanetriyl)tripropanamide

4-(2-carboxyethyl)-4-nitroheptanedioic acid

Downstream raw materials:

N,N',N''-trioctadecyl-3,3',3''-[(4-carboxyphenyl-carbonylamino)methanetriyl]tripropanamide