4-(4-(4-(3-(3-(4-(1H-indol-3-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrol-3-yl)-indol-1-yl)-propyl)-(1,2,3)triazol-1-yl)-phenyl)-propionic acid

Base Information

Chemical Name:4-(4-(4-(3-(3-(4-(1H-indol-3-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrol-3-yl)-indol-1-yl)-propyl)-(1,2,3)triazol-1-yl)-phenyl)-propionic acid
CAS No.:1262304-22-2
Molecular Formula:C₃₄H₂₈N₆O₄
Molecular Weight:584.634
Hs Code.:

Synonyms:4-(4-(4-(3-(3-(4-(1H-indol-3-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrol-3-yl)-indol-1-yl)-propyl)-(1,2,3)triazol-1-yl)-phenyl)-propionic acid

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Chemical Property of 4-(4-(4-(3-(3-(4-(1H-indol-3-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrol-3-yl)-indol-1-yl)-propyl)-(1,2,3)triazol-1-yl)-phenyl)-propionic acid

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Technology Process of 4-(4-(4-(3-(3-(4-(1H-indol-3-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrol-3-yl)-indol-1-yl)-propyl)-(1,2,3)triazol-1-yl)-phenyl)-propionic acid

There total 4 articles about 4-(4-(4-(3-(3-(4-(1H-indol-3-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrol-3-yl)-indol-1-yl)-propyl)-(1,2,3)triazol-1-yl)-phenyl)-propionic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1262304-11-9
C₂₅H₁₉N₃O₂

: 103489-31-2
β-(4-azidophenyl)-propanoic acid

: 1262304-22-2
4-(4-(4-(3-(3-(4-(1H-indol-3-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrol-3-yl)-indol-1-yl)-propyl)-(1,2,3)triazol-1-yl)-phenyl)-propionic acid

Guidance literature:: With copper(ll) sulfate pentahydrate; sodium L-ascorbate; In water; acetonitrile; tert-butyl alcohol; at 100 ℃; for 0.333333h; Microwave irradiation; Combinatorial reaction / High throughput screening (HTS);
DOI:10.1039/c0cc01166e

Reference yield:

: 942434-83-5
C₁₅H₁₆N₂O

: 1262304-22-2
4-(4-(4-(3-(3-(4-(1H-indol-3-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrol-3-yl)-indol-1-yl)-propyl)-(1,2,3)triazol-1-yl)-phenyl)-propionic acid

Guidance literature:: Multi-step reaction with 2 steps

1: potassium tert-butylate / tetrahydrofuran / 4 h / 0 - 20 °C

2: copper(ll) sulfate pentahydrate; sodium L-ascorbate / water; acetonitrile; tert-butyl alcohol / 0.33 h / 100 °C / Microwave irradiation; Combinatorial reaction / High throughput screening (HTS)

With copper(ll) sulfate pentahydrate; potassium tert-butylate; sodium L-ascorbate; In tetrahydrofuran; water; acetonitrile; tert-butyl alcohol;
DOI:10.1039/c0cc01166e

Reference yield:

: 18372-22-0
2-(3-indolyl)oxoacetic acid methyl ester

: 1262304-22-2
4-(4-(4-(3-(3-(4-(1H-indol-3-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrol-3-yl)-indol-1-yl)-propyl)-(1,2,3)triazol-1-yl)-phenyl)-propionic acid

Guidance literature:: Multi-step reaction with 2 steps

1: potassium tert-butylate / tetrahydrofuran / 4 h / 0 - 20 °C

2: copper(ll) sulfate pentahydrate; sodium L-ascorbate / water; acetonitrile; tert-butyl alcohol / 0.33 h / 100 °C / Microwave irradiation; Combinatorial reaction / High throughput screening (HTS)

With copper(ll) sulfate pentahydrate; potassium tert-butylate; sodium L-ascorbate; In tetrahydrofuran; water; acetonitrile; tert-butyl alcohol;
DOI:10.1039/c0cc01166e