C₁₅H₁₆O₆

Base Information

• Chemical Name: C₁₅H₁₆O₆
• CAS No.: 1612771-50-2
• Molecular Formula: C₁₅H₁₆O₆
• Molecular Weight: 292.288
• Mol file: 1612771-50-2.mol

Synonyms:C₁₅H₁₆O₆

Chemical Property of C₁₅H₁₆O₆

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of C₁₅H₁₆O₆

There total 1 articles about C₁₅H₁₆O₆ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

(furan-2-yloxy)-trimethylsilane (61550-02-5) + C11H12O4 (1612771-49-9) → C15H16O6 (1612771-50-2)

Guidance literature:

With zinc trifluoromethanesulfonate; In tetrahydrofuran; water; at 0 ℃; for 12h; Inert atmosphere;

DOI:10.1021/ol501423t

Reference yield: 75.0%

C15H16O6 (1612771-50-2) → C15H15IO6 (1612771-51-3)

Guidance literature:

With N-iodo-succinimide; methanesulfonic acid; In acetic acid; at 20 ℃; for 6h; Inert atmosphere;

DOI:10.1021/ol501423t

Reference yield:

C15H16O6 (1612771-50-2) → C26H20O5Se

Guidance literature:

Multi-step reaction with 13 steps

1.1: N-iodo-succinimide; methanesulfonic acid / acetic acid / 6 h / 20 °C / Inert atmosphere

2.1: bis-triphenylphosphine-palladium(II) chloride; 1,2,2,6,6-pentamethylpiperidine / N,N-dimethyl-formamide / 12 h / 130 °C / Inert atmosphere

3.1: sodium hydride / dimethyl sulfoxide; mineral oil / 4 h / 20 °C / Inert atmosphere

4.1: 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride / benzene / 5 h / 80 °C / Inert atmosphere

5.1: sodium tetrahydroborate / ethanol / 1 h / 20 °C / Inert atmosphere

6.1: toluene-4-sulfonic acid / toluene / 1 h / 80 °C / Inert atmosphere

7.1: diethylzinc; trifluoroacetic acid / dichloromethane; hexane / 0.33 h / 0 °C / Inert atmosphere

7.2: 12 h / 20 °C / Inert atmosphere

8.1: boron trichloride / dichloromethane / 0.5 h / 20 °C / Inert atmosphere

9.1: sodium hydride / tetrahydrofuran; mineral oil / 0.5 h / 20 °C / Inert atmosphere

10.1: bis-triphenylphosphine-palladium(II) chloride; lithium chloride / N,N-dimethyl-formamide / 12 h / 100 °C / Inert atmosphere

11.1: pyridine hydrogenfluoride / acetonitrile / 0.5 h / 20 °C / Inert atmosphere

12.1: triethylamine / dichloromethane / 0.5 h / 0 °C / Inert atmosphere

13.1: dichloromethane / 1 h / 0 °C / Inert atmosphere

With 1,2,2,6,6-pentamethylpiperidine; bis-triphenylphosphine-palladium(II) chloride; sodium tetrahydroborate; N-iodo-succinimide; methanesulfonic acid; 2,2'-azobis(isobutyronitrile); diethylzinc; tri-n-butyl-tin hydride; boron trichloride; sodium hydride; toluene-4-sulfonic acid; pyridine hydrogenfluoride; triethylamine; trifluoroacetic acid; lithium chloride; In tetrahydrofuran; ethanol; hexane; dichloromethane; acetic acid; dimethyl sulfoxide; N,N-dimethyl-formamide; toluene; acetonitrile; mineral oil; benzene; 2.1: |Heck Reaction / 4.1: |Dowd Ring Expansion / 10.1: |Stille Cross Coupling;

DOI:10.1021/ol501423t

upstream raw materials:

(furan-2-yloxy)-trimethylsilane

C₁₁H₁₂O₄

Downstream raw materials:

C₁₅H₁₅IO₆