1-(Piperidin-4-yl)urea hydrochloride

Base Information

• Chemical Name: 1-(Piperidin-4-yl)urea hydrochloride
• CAS No.: 61220-33-5
• Molecular Formula: C₆H₁₃N₃O
• Molecular Weight: 143.189
• Hs Code.: 2933399090
• European Community (EC) Number: 833-880-7,674-796-9
• DSSTox Substance ID: DTXSID20590473
• Mol file: 61220-33-5.mol

Synonyms:61220-33-5;1-(piperidin-4-yl)urea hydrochloride;(piperidin-4-yl)urea hydrochloride;1190194-60-5;piperidin-4-yl-urea hcl;Piperidin-4-yl-urea hydrochloride;piperidin-4-ylurea;hydrochloride;MFCD08448238;piperidin-4-yl-urea-hydrochloride;Urea,N-4-piperidinyl-;Piperidin-4-yl-urea x HCl;SCHEMBL1017673;DTXSID20590473;QRTZJALNMZMDSM-UHFFFAOYSA-N;1-(PIPERIDIN-4-YL)UREA HCL;AKOS015996748;AT22990;SB41164;CS-0257648;EN300-67478;N-Piperidin-4-ylurea--hydrogen chloride (1/1);A923975;F2167-4141;Z1272096623

Chemical Property of 1-(Piperidin-4-yl)urea hydrochloride

Chemical Property:

• Vapor Pressure: 0.000982mmHg at 25°C
• Melting Point: 178-185°C
• Boiling Point: 297.9°C at 760 mmHg
• Flash Point: 134°C
• PSA: 67.15000
• LogP: 1.62870
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 179.0825398
• Heavy Atom Count: 11
• Complexity: 120

Purity/Quality:

97% ^*data from raw suppliers

Piperidin-4-yl-ureaHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CNCCC1NC(=O)N.Cl

Technology Process of 1-(Piperidin-4-yl)urea hydrochloride

There total 1 articles about 1-(Piperidin-4-yl)urea hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ piperidin-4-yl-urea (61220-33-5)

Guidance literature:

1-Benzyl-4-ureido-piperidin, Hydrierung an Pd/C;

Reference yield:

piperidine (110-89-4) + 1-(4-acetylamino-5-chloro-2-(3,5-dimethoxy-benzyloxy)phenyl]-5-chloropentan-1-one (166816-05-3) + piperidin-4-yl-urea (61220-33-5) → 1-?4-amino-5-chloro-2-(3,5-dimethoxy-benzyloxy)[phenyl]-5-[4-(aminocarbonyl)aminopiperidin-1-yl]pentan-1-one hydrochloride

Guidance literature:

Reference yield:

piperidin-4-yl-urea (61220-33-5) + 2-[4-(phenylmethyl)phenoxy]ethyl 4-methylbenzenesulfonate (60225-65-2) → N-[1-[2-[4-(phenylmethyl)phenoxy]ethyl]piperidin-4-yl]urea

Guidance literature:

With tetra-(n-butyl)ammonium iodide; potassium carbonate; In N,N-dimethyl-formamide; Heating;

DOI:10.1016/S0960-894X(02)00760-6