N^α-p-Toluenesulfonyl-S-benzylcysteinyl-tyrosyl-isoleucyl-glutaminyl-asparaginyl-S-benzylcysteinyl-prolyl-tert-leucyl-glycine Amide

Base Information

• Chemical Name: N^α-p-Toluenesulfonyl-S-benzylcysteinyl-tyrosyl-isoleucyl-glutaminyl-asparaginyl-S-benzylcysteinyl-prolyl-tert-leucyl-glycine Amide
• CAS No.: 82152-67-8
• Molecular Formula: C₆₄H₈₆N₁₂O₁₄S₃
• Molecular Weight: 1343.66

Synonyms:N^α-p-Toluenesulfonyl-S-benzylcysteinyl-tyrosyl-isoleucyl-glutaminyl-asparaginyl-S-benzylcysteinyl-prolyl-tert-leucyl-glycine Amide

Chemical Property of N^α-p-Toluenesulfonyl-S-benzylcysteinyl-tyrosyl-isoleucyl-glutaminyl-asparaginyl-S-benzylcysteinyl-prolyl-tert-leucyl-glycine Amide

Chemical Property:

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Technology Process of N^α-p-Toluenesulfonyl-S-benzylcysteinyl-tyrosyl-isoleucyl-glutaminyl-asparaginyl-S-benzylcysteinyl-prolyl-tert-leucyl-glycine Amide

There total 1 articles about N^α-p-Toluenesulfonyl-S-benzylcysteinyl-tyrosyl-isoleucyl-glutaminyl-asparaginyl-S-benzylcysteinyl-prolyl-tert-leucyl-glycine Amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

C51H64N8O12S3 (70397-61-4) + Prolyl-tert-leucyl-glycinamide (62965-63-3) → Nα-p-Toluenesulfonyl-S-benzylcysteinyl-tyrosyl-isoleucyl-glutaminyl-asparaginyl-S-benzylcysteinyl-prolyl-tert-leucyl-glycine Amide (82152-67-8)

Guidance literature:

With 2,3,4,5,6-pentafluorophenol; benzotriazol-1-ol; dicyclohexyl-carbodiimide; In N,N-dimethyl-formamide; for 72h; Ambient temperature;

DOI:10.1135/cccc19820689

Reference yield:

Nα-p-Toluenesulfonyl-S-benzylcysteinyl-tyrosyl-isoleucyl-glutaminyl-asparaginyl-S-benzylcysteinyl-prolyl-tert-leucyl-glycine Amide (82152-67-8) → <8-Tert-leucine>oxytocin (84059-95-0)

Guidance literature:

Yield given. Multistep reaction; 1) Na/NH₃; 2) air, 2 h;

DOI:10.1135/cccc19820689

upstream raw materials:

C₅₁H₆₄N₈O₁₂S₃

Prolyl-tert-leucyl-glycinamide

Downstream raw materials:

<8-Tert-leucine>oxytocin

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