tert-butyl 3-(3-(1-(cyclopropylmethyl)-1H-pyrazol-4-yl)phenethoxy)propanoate

Base Information

Chemical Name:tert-butyl 3-(3-(1-(cyclopropylmethyl)-1H-pyrazol-4-yl)phenethoxy)propanoate
CAS No.:1201641-15-7
Molecular Formula:C₂₂H₃₀N₂O₃
Molecular Weight:370.492
Hs Code.:

Synonyms:tert-butyl 3-(3-(1-(cyclopropylmethyl)-1H-pyrazol-4-yl)phenethoxy)propanoate

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Chemical Property of tert-butyl 3-(3-(1-(cyclopropylmethyl)-1H-pyrazol-4-yl)phenethoxy)propanoate

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Technology Process of tert-butyl 3-(3-(1-(cyclopropylmethyl)-1H-pyrazol-4-yl)phenethoxy)propanoate

There total 3 articles about tert-butyl 3-(3-(1-(cyclopropylmethyl)-1H-pyrazol-4-yl)phenethoxy)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1000801-75-1
1-(cyclopropylmethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole

: 1201640-34-7
tert-butyl 3-[2-(3-bromophenyl)ethoxy]propanoate

: 1201641-15-7
tert-butyl 3-(3-(1-(cyclopropylmethyl)-1H-pyrazol-4-yl)phenethoxy)propanoate

Guidance literature:: With potassium carbonate; dichloro[1,1'-bis(di-t-butylphosphino)ferrocene]palladium(II); In water; acetonitrile; at 80 ℃; for 1h;

Reference yield:

: 1663-39-4,25232-27-3
tert-Butyl acrylate

: 1201641-15-7
tert-butyl 3-(3-(1-(cyclopropylmethyl)-1H-pyrazol-4-yl)phenethoxy)propanoate

Guidance literature:: Multi-step reaction with 2 steps

1: N-benzyl-trimethylammonium hydroxide / methanol; toluene / 24 h

2: potassium carbonate / dichloro[1,1'-bis(di-t-butylphosphino)ferrocene]palladium(II) / water; acetonitrile / 1 h / 80 °C

With N-benzyl-trimethylammonium hydroxide; potassium carbonate; dichloro[1,1'-bis(di-t-butylphosphino)ferrocene]palladium(II); In methanol; water; toluene; acetonitrile; 2: Suzuki Coupling;

Reference yield:

: 28229-69-8
2-(3-bromophenyl)ethan-1-ol

: 1201641-15-7
tert-butyl 3-(3-(1-(cyclopropylmethyl)-1H-pyrazol-4-yl)phenethoxy)propanoate

Guidance literature:: Multi-step reaction with 2 steps

1: N-benzyl-trimethylammonium hydroxide / methanol; toluene / 24 h

2: potassium carbonate / dichloro[1,1'-bis(di-t-butylphosphino)ferrocene]palladium(II) / water; acetonitrile / 1 h / 80 °C

With N-benzyl-trimethylammonium hydroxide; potassium carbonate; dichloro[1,1'-bis(di-t-butylphosphino)ferrocene]palladium(II); In methanol; water; toluene; acetonitrile; 2: Suzuki Coupling;