N-(1-(but-3-enyl)-5-fluoro-1H-indol-2-yl)-N-(4-fluoro-2-iodophenyl)-4-methylbenzenesulfonamide

Base Information

• Chemical Name: N-(1-(but-3-enyl)-5-fluoro-1H-indol-2-yl)-N-(4-fluoro-2-iodophenyl)-4-methylbenzenesulfonamide
• CAS No.: 1599476-86-4
• Molecular Formula: C₂₅H₂₁F₂IN₂O₂S
• Molecular Weight: 578.421
• Mol file: 1599476-86-4.mol

Synonyms:N-(1-(but-3-enyl)-5-fluoro-1H-indol-2-yl)-N-(4-fluoro-2-iodophenyl)-4-methylbenzenesulfonamide

Chemical Property of N-(1-(but-3-enyl)-5-fluoro-1H-indol-2-yl)-N-(4-fluoro-2-iodophenyl)-4-methylbenzenesulfonamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(1-(but-3-enyl)-5-fluoro-1H-indol-2-yl)-N-(4-fluoro-2-iodophenyl)-4-methylbenzenesulfonamide

There total 1 articles about N-(1-(but-3-enyl)-5-fluoro-1H-indol-2-yl)-N-(4-fluoro-2-iodophenyl)-4-methylbenzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C12H12FN (1341721-59-2) + N-(4-fluorophenyl)-4-methylbenzenesulfonamide (727-31-1) → N-(1-(but-3-enyl)-5-fluoro-1H-indol-2-yl)-N-(4-fluoro-2-iodophenyl)-4-methylbenzenesulfonamide (1599476-86-4)

Guidance literature:

With iodine; caesium carbonate; In acetonitrile; at 20 ℃; for 4h; Inert atmosphere;

DOI:10.1039/c4ob00140k

Reference yield: 61.0%

N-(1-(but-3-enyl)-5-fluoro-1H-indol-2-yl)-N-(4-fluoro-2-iodophenyl)-4-methylbenzenesulfonamide (1599476-86-4) → C25H20F2N2O2S (1599476-80-8)

Guidance literature:

With bis-triphenylphosphine-palladium(II) chloride; triethylamine; In N,N-dimethyl-formamide; at 110 ℃; for 4h; regioselective reaction; Inert atmosphere;

DOI:10.1039/c4ob00140k

upstream raw materials:

C₁₂H₁₂FN

N-(4-fluorophenyl)-4-methylbenzenesulfonamide

Downstream raw materials:

C₂₅H₂₀F₂N₂O₂S