2-Benzenesulfonyl-2-((Z)-4-hydroxy-but-2-enyl)-cyclododecanone

Base Information

• Chemical Name: 2-Benzenesulfonyl-2-((Z)-4-hydroxy-but-2-enyl)-cyclododecanone
• CAS No.: 81238-29-1
• Molecular Formula: C₂₂H₃₂O₄S
• Molecular Weight: 392.56
• Mol file: 81238-29-1.mol

Synonyms:2-Benzenesulfonyl-2-((Z)-4-hydroxy-but-2-enyl)-cyclododecanone

Chemical Property of 2-Benzenesulfonyl-2-((Z)-4-hydroxy-but-2-enyl)-cyclododecanone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Benzenesulfonyl-2-((Z)-4-hydroxy-but-2-enyl)-cyclododecanone

There total 4 articles about 2-Benzenesulfonyl-2-((Z)-4-hydroxy-but-2-enyl)-cyclododecanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

Acetic acid (Z)-4-(1-benzenesulfonyl-2-oxo-cyclododecyl)-but-2-enyl ester (81238-25-7) → 2-Benzenesulfonyl-2-((Z)-4-hydroxy-but-2-enyl)-cyclododecanone (81238-29-1)

Guidance literature:

With hydrogenchloride; In ethanol; for 8h; Heating;

DOI:10.1039/c39810001123

Reference yield:

2-benzenesulfonylcyclododecanone (67886-41-3) → 2-Benzenesulfonyl-2-((Z)-4-hydroxy-but-2-enyl)-cyclododecanone (81238-29-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 86 percent / NaH, NaI / 1,2-dimethoxy-ethane / 65 - 80 °C

2: 97 percent / 10percent aq. HCl / ethanol / 8 h / Heating

With hydrogenchloride; sodium hydride; sodium iodide; In 1,2-dimethoxyethane; ethanol;

DOI:10.1039/c39810001123

Reference yield:

2-bromocyclododecan-1-one (31236-94-9) → 2-Benzenesulfonyl-2-((Z)-4-hydroxy-but-2-enyl)-cyclododecanone (81238-29-1)

Guidance literature:

Multi-step reaction with 3 steps

1: dimethylformamide

2: 86 percent / NaH, NaI / 1,2-dimethoxy-ethane / 65 - 80 °C

3: 97 percent / 10percent aq. HCl / ethanol / 8 h / Heating

With hydrogenchloride; sodium hydride; sodium iodide; In 1,2-dimethoxyethane; ethanol; N,N-dimethyl-formamide;

DOI:10.1039/c39810001123

upstream raw materials:

Acetic acid (Z)-4-(1-benzenesulfonyl-2-oxo-cyclododecyl)-but-2-enyl ester

2-benzenesulfonylcyclododecanone

2-bromocyclododecan-1-one

sodium benzenesulfonate

Downstream raw materials:

(Z)-13-Benzenesulfonyl-oxacycloheptadec-15-en-2-one