2-(trimethylsilyl)ethyl (methyl 5-acetamido-4,7,8-tri-O-acetyl-9-azido-3,5,9-trideoxy-D-glycero-α-D-galacto-2-nonulopyranosynate)-(2->3)-(6-O-benzoyl-β-D-galactopyranosyl)-(1->3)-2,6-di-O-(4-methoxybenzyl)-β-D-galactopyranoside

Base Information

• Chemical Name: 2-(trimethylsilyl)ethyl (methyl 5-acetamido-4,7,8-tri-O-acetyl-9-azido-3,5,9-trideoxy-D-glycero-α-D-galacto-2-nonulopyranosynate)-(2->3)-(6-O-benzoyl-β-D-galactopyranosyl)-(1->3)-2,6-di-O-(4-methoxybenzyl)-β-D-galactopyranoside
• CAS No.: 1123178-56-2
• Molecular Formula: C₅₈H₇₈N₄O₂₄Si
• Molecular Weight: 1243.36
• Mol file: 1123178-56-2.mol

Synonyms:2-(trimethylsilyl)ethyl (methyl 5-acetamido-4,7,8-tri-O-acetyl-9-azido-3,5,9-trideoxy-D-glycero-α-D-galacto-2-nonulopyranosynate)-(2->3)-(6-O-benzoyl-β-D-galactopyranosyl)-(1->3)-2,6-di-O-(4-methoxybenzyl)-β-D-galactopyranoside

Chemical Property of 2-(trimethylsilyl)ethyl (methyl 5-acetamido-4,7,8-tri-O-acetyl-9-azido-3,5,9-trideoxy-D-glycero-α-D-galacto-2-nonulopyranosynate)-(2->3)-(6-O-benzoyl-β-D-galactopyranosyl)-(1->3)-2,6-di-O-(4-methoxybenzyl)-β-D-galactopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

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Useful:

Technology Process of 2-(trimethylsilyl)ethyl (methyl 5-acetamido-4,7,8-tri-O-acetyl-9-azido-3,5,9-trideoxy-D-glycero-α-D-galacto-2-nonulopyranosynate)-(2->3)-(6-O-benzoyl-β-D-galactopyranosyl)-(1->3)-2,6-di-O-(4-methoxybenzyl)-β-D-galactopyranoside

There total 1 articles about 2-(trimethylsilyl)ethyl (methyl 5-acetamido-4,7,8-tri-O-acetyl-9-azido-3,5,9-trideoxy-D-glycero-α-D-galacto-2-nonulopyranosynate)-(2->3)-(6-O-benzoyl-β-D-galactopyranosyl)-(1->3)-2,6-di-O-(4-methoxybenzyl)-β-D-galactopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.0%

methyl (methyl 5-acetamido-4,7,8-tri-O-acetyl-9-azido-2-thio-3,5,9-trideoxy-D-glycero-D-galacto-2-nonulopyranosid)onate (1123178-55-1) + 2-(trimethylsilyl)ethyl (6-O-benzoyl-β-D-galactopyranosyl)-(1->3)-2,6-di-O-(4-methoxybenzyl)-β-D-galactopyranoside (1123178-54-0) → C58H78N4O24Si (1194454-31-3) + 2-(trimethylsilyl)ethyl (methyl 5-acetamido-4,7,8-tri-O-acetyl-9-azido-3,5,9-trideoxy-D-glycero-α-D-galacto-2-nonulopyranosynate)-(2->3)-(6-O-benzoyl-β-D-galactopyranosyl)-(1->3)-2,6-di-O-(4-methoxybenzyl)-β-D-galactopyranoside (1123178-56-2)

Guidance literature:

methyl (methyl 5-acetamido-4,7,8-tri-O-acetyl-9-azido-2-thio-3,5,9-trideoxy-D-glycero-D-galacto-2-nonulopyranosid)onate; 2-(trimethylsilyl)ethyl (6-O-benzoyl-β-D-galactopyranosyl)-(1->3)-2,6-di-O-(4-methoxybenzyl)-β-D-galactopyranoside; In acetonitrile; at 20 ℃; for 6h; Inert atmosphere; Molecular sieve;

With dimethyl(methylthio)sulfonium triflate; In acetonitrile; at 0 ℃; for 16h; Inert atmosphere; Molecular sieve;

DOI:10.1021/jm801058n

Reference yield: 87.0%

2-(trimethylsilyl)ethyl (methyl 5-acetamido-4,7,8-tri-O-acetyl-9-azido-3,5,9-trideoxy-D-glycero-α-D-galacto-2-nonulopyranosynate)-(2->3)-(6-O-benzoyl-β-D-galactopyranosyl)-(1->3)-2,6-di-O-(4-methoxybenzyl)-β-D-galactopyranoside (1123178-56-2) + acetic anhydride (108-24-7) → 2-(trimethylsilyl)ethyl (methyl 5-acetamido-4,7,8-tri-O-acetyl-9-azido-3,5,9-trideoxy-D-glycero-α-D-galacto-2-nonulopyranosynate)-(2->3)-(2,4-di-O-acetyl-6-O-benzoyl-β-D-galactopyranosyl)-(1->3)-4-O-acetyl-2,6-di-O-(p-methoxybenzyl)-β-D-galactopyranoside

Guidance literature:

With pyridine; dmap; at 0 - 20 ℃; Inert atmosphere;

DOI:10.1021/jm801058n

upstream raw materials:

methyl (methyl 5-acetamido-4,7,8-tri-O-acetyl-9-azido-2-thio-3,5,9-trideoxy-D-glycero-D-galacto-2-nonulopyranosid)onate

2-(trimethylsilyl)ethyl (6-O-benzoyl-β-D-galactopyranosyl)-(1->3)-2,6-di-O-(4-methoxybenzyl)-β-D-galactopyranoside