(4S)-4-benzyl-3-{[2-({6-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]pyridin-3-yl}methyl)tetrahydro furan-2-yl]carbonyl}-1,3-oxazolidin-2-one

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Chemical Name:(4S)-4-benzyl-3-{[2-({6-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]pyridin-3-yl}methyl)tetrahydro furan-2-yl]carbonyl}-1,3-oxazolidin-2-one
CAS No.:1058722-13-6
Molecular Formula:C₃₃H₃₃N₃O₆
Molecular Weight:567.642
Hs Code.:

Synonyms:(4S)-4-benzyl-3-{[2-({6-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]pyridin-3-yl}methyl)tetrahydro furan-2-yl]carbonyl}-1,3-oxazolidin-2-one

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Chemical Property of (4S)-4-benzyl-3-{[2-({6-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]pyridin-3-yl}methyl)tetrahydro furan-2-yl]carbonyl}-1,3-oxazolidin-2-one

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Technology Process of (4S)-4-benzyl-3-{[2-({6-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]pyridin-3-yl}methyl)tetrahydro furan-2-yl]carbonyl}-1,3-oxazolidin-2-one

There total 2 articles about (4S)-4-benzyl-3-{[2-({6-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]pyridin-3-yl}methyl)tetrahydro furan-2-yl]carbonyl}-1,3-oxazolidin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 784149-88-8
(4S)-4-benzyl-3-(tetrahydrofuran-2-ylcarbonyl)-1,3-oxazolidin-2-one

: 784149-40-2
5-(iodomethyl)-2-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]pyridine

: 1058722-13-6
(4S)-4-benzyl-3-{[2-({6-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]pyridin-3-yl}methyl)tetrahydro furan-2-yl]carbonyl}-1,3-oxazolidin-2-one

Guidance literature:: (4S)-4-benzyl-3-(tetrahydrofuran-2-ylcarbonyl)-1,3-oxazolidin-2-one; With sodium hexamethyldisilazane; In tetrahydrofuran; at -50 ℃; for 0.75h;

5-(iodomethyl)-2-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]pyridine; In tetrahydrofuran; at -50 ℃; for 1.5h;

Reference yield: 90.0%

: 784149-88-8
(4S)-4-benzyl-3-(tetrahydrofuran-2-ylcarbonyl)-1,3-oxazolidin-2-one

: 784149-40-2
5-(iodomethyl)-2-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]pyridine

: 1070-89-9
sodium hexamethyldisilazane

: 1058722-13-6
(4S)-4-benzyl-3-{[2-({6-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]pyridin-3-yl}methyl)tetrahydro furan-2-yl]carbonyl}-1,3-oxazolidin-2-one

Guidance literature:: In tetrahydrofuran;

Reference yield:

: 1058722-13-6
(4S)-4-benzyl-3-{[2-({6-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]pyridin-3-yl}methyl)tetrahydro furan-2-yl]carbonyl}-1,3-oxazolidin-2-one

: 2-({6-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]pyridin-3-yl}methyl)tetrahydrofuran-2-carboxylic acid

Guidance literature:: (4S)-4-benzyl-3-{[2-({6-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]pyridin-3-yl}methyl)tetrahydro furan-2-yl]carbonyl}-1,3-oxazolidin-2-one; With lithium hydroxide; water; In tetrahydrofuran; methanol; at 20 - 50 ℃; for 52.5h;

pH=5; Acidic aqueous solution;