C₇₁H₈₀N₆O₈

Base Information

• Chemical Name: C₇₁H₈₀N₆O₈
• CAS No.: 1326779-12-7
• Molecular Formula: C₇₁H₈₀N₆O₈
• Molecular Weight: 1145.45
• Mol file: 1326779-12-7.mol

Synonyms:C₇₁H₈₀N₆O₈

Chemical Property of C₇₁H₈₀N₆O₈

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₇₁H₈₀N₆O₈

There total 7 articles about C₇₁H₈₀N₆O₈ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

C34H43N3O4 (1326778-95-3) + C37H39N3O5 → C71H80N6O8 (1326779-12-7)

Guidance literature:

With triethylamine; HATU; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 72h; Inert atmosphere;

DOI:10.1002/ejoc.201100232

Reference yield:

3-(bromomethyl)benzoyl bromide (209743-33-9) → C71H80N6O8 (1326779-12-7)

Guidance literature:

Multi-step reaction with 5 steps

1.1: triethylamine / tetrahydrofuran / 1 h / 0 °C / Inert atmosphere

1.2: 20 °C / Inert atmosphere

2.1: triethylamine / tetrahydrofuran / 1 h / 0 °C / Inert atmosphere

2.2: 20 °C / Inert atmosphere

3.1: triethylamine / dichloromethane / 1 h / 0 °C / Inert atmosphere

4.1: trifluoroacetic acid / dichloromethane / 3 h / 0 °C

5.1: triethylamine; HATU / N,N-dimethyl-formamide / 72 h / 0 - 20 °C / Inert atmosphere

With triethylamine; HATU; trifluoroacetic acid; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;

DOI:10.1002/ejoc.201100232

Reference yield:

tert-butyl 3-[(ethylamino)methyl]benzoate (1326778-93-1) → C71H80N6O8 (1326779-12-7)

Guidance literature:

Multi-step reaction with 5 steps

1.1: triethylamine / tetrahydrofuran / 1 h / 0 °C / Inert atmosphere

1.2: 20 °C / Inert atmosphere

2.1: triethylamine / tetrahydrofuran / 1 h / 0 °C / Inert atmosphere

2.2: 20 °C / Inert atmosphere

3.1: triethylamine / dichloromethane / 1 h / 0 °C / Inert atmosphere

4.1: trifluoroacetic acid / dichloromethane / 3 h / 0 °C

5.1: triethylamine; HATU / N,N-dimethyl-formamide / 72 h / 0 - 20 °C / Inert atmosphere

With triethylamine; HATU; trifluoroacetic acid; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;

DOI:10.1002/ejoc.201100232

upstream raw materials:

tert-butyl 3-[(ethylamino)methyl]benzoate

C₂₄H₃₂N₂O₃

C₃₄H₄₃N₃O₄

C₄₁H₄₇N₃O₅

Downstream raw materials:

C₆₇H₇₂N₆O₈