2-methoxy-3',4'-methylenedioxy-5,6'-diformyldiphenyl ether

Base Information

• Chemical Name: 2-methoxy-3',4'-methylenedioxy-5,6'-diformyldiphenyl ether
• CAS No.: 131814-93-2
• Molecular Formula: C₁₆H₁₂O₆
• Molecular Weight: 300.268
• Mol file: 131814-93-2.mol

Synonyms:2-methoxy-3',4'-methylenedioxy-5,6'-diformyldiphenyl ether

Chemical Property of 2-methoxy-3',4'-methylenedioxy-5,6'-diformyldiphenyl ether

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 2-methoxy-3',4'-methylenedioxy-5,6'-diformyldiphenyl ether

There total 2 articles about 2-methoxy-3',4'-methylenedioxy-5,6'-diformyldiphenyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

isovanillin (621-59-0) + 6-bromo-3,4-methylenedioxybenzaldehyde (15930-53-7) → 2-methoxy-3',4'-methylenedioxy-5,6'-diformyldiphenyl ether (131814-93-2)

Guidance literature:

With potassium carbonate; copper(II) oxide; In pyridine; at 145 - 150 ℃; for 24h;

Reference yield:

piperonal (120-57-0,30024-74-9) → 2-methoxy-3',4'-methylenedioxy-5,6'-diformyldiphenyl ether (131814-93-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 90 percent / Br₂, acetic acid / 20 h / Ambient temperature

2: 50 percent / CuO, K₂CO₃, pyridine / 24 h / 145 - 150 °C

With pyridine; bromine; potassium carbonate; acetic acid; copper(II) oxide;

DOI:10.1007/BF00629645

Reference yield: 45.0%

2-methoxy-3',4'-methylenedioxy-5,6'-diformyldiphenyl ether (131814-93-2) → 2-methoxy-3',4'-methylenedioxy-5-formyl-,6-bromodiphenyl ether (131814-94-3)

Guidance literature:

With bromine; In acetic acid; for 4h; Ambient temperature;

upstream raw materials:

isovanillin

6-bromo-3,4-methylenedioxybenzaldehyde

piperonal

Downstream raw materials:

2-methoxy-3',4'-methylenedioxy-5-formyl-,6-bromodiphenyl ether

5'',6'-bis(3,4-dimethoxyphenethylaminomethyl)-2''-methoxy-3',4'-methylenedioxydiphenyl ether