2-nitro-4-[(triisopropylsilanyl)ethynyl]-1-(trimethylsilanylethynyl)benzene

Base Information

Chemical Name:2-nitro-4-[(triisopropylsilanyl)ethynyl]-1-(trimethylsilanylethynyl)benzene
CAS No.:914673-81-7
Molecular Formula:C₂₂H₃₃NO₂Si₂
Molecular Weight:399.681
Hs Code.:

Synonyms:2-nitro-4-[(triisopropylsilanyl)ethynyl]-1-(trimethylsilanylethynyl)benzene

Suppliers and Price of 2-nitro-4-[(triisopropylsilanyl)ethynyl]-1-(trimethylsilanylethynyl)benzene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 2-nitro-4-[(triisopropylsilanyl)ethynyl]-1-(trimethylsilanylethynyl)benzene

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of 2-nitro-4-[(triisopropylsilanyl)ethynyl]-1-(trimethylsilanylethynyl)benzene

There total 4 articles about 2-nitro-4-[(triisopropylsilanyl)ethynyl]-1-(trimethylsilanylethynyl)benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

: 89343-06-6
tris-iso-propylsilyl acetylene

: 676251-39-1
1-bromo-3-nitro-4-(trimethylsilylethynyl)benzene

: 914673-81-7
2-nitro-4-[(triisopropylsilanyl)ethynyl]-1-(trimethylsilanylethynyl)benzene

Guidance literature:: With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; diisopropylamine; In tetrahydrofuran; at 20 ℃; for 16h;
DOI:10.1002/ejoc.200600336

Reference yield:

: 106-37-6
1.4-dibromobenzene

: 914673-81-7
2-nitro-4-[(triisopropylsilanyl)ethynyl]-1-(trimethylsilanylethynyl)benzene

Guidance literature:: Multi-step reaction with 3 steps

1: 60 percent / HNO₃; H₂SO₄ / 95 °C

2: 53 percent / Pd(PPh₃)2Cl₂; CuI; iPr₂NH / tetrahydrofuran / 2 h / 20 °C

3: 63 percent / Pd(PPh₃)2Cl₂; CuI; iPr₂NH / tetrahydrofuran / 16 h / 20 °C

With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; sulfuric acid; nitric acid; diisopropylamine; In tetrahydrofuran; 2: Sonogashira coupling / 3: Sonogashira coupling;
DOI:10.1002/ejoc.200600336

Reference yield:

: 3460-18-2
1,4-dibromo-2-nitrobenzene

: 914673-81-7
2-nitro-4-[(triisopropylsilanyl)ethynyl]-1-(trimethylsilanylethynyl)benzene

Guidance literature:: Multi-step reaction with 2 steps

1: 53 percent / Pd(PPh₃)2Cl₂; CuI; iPr₂NH / tetrahydrofuran / 2 h / 20 °C

2: 63 percent / Pd(PPh₃)2Cl₂; CuI; iPr₂NH / tetrahydrofuran / 16 h / 20 °C

With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; diisopropylamine; In tetrahydrofuran; 1: Sonogashira coupling / 2: Sonogashira coupling;
DOI:10.1002/ejoc.200600336