N₁,N₈-bis(3,5-bis(trifluoromethyl)phenyl)-3,6-di-tert-butyl-9Hcarbazole-1,8-disulfonamide

Base Information

• Chemical Name: N₁,N₈-bis(3,5-bis(trifluoromethyl)phenyl)-3,6-di-tert-butyl-9Hcarbazole-1,8-disulfonamide
• CAS No.: 1350814-44-6
• Molecular Formula: C₃₆H₃₁F₁₂N₃O₄S₂
• Molecular Weight: 861.773
• Mol file: 1350814-44-6.mol

Synonyms:N₁,N₈-bis(3,5-bis(trifluoromethyl)phenyl)-3,6-di-tert-butyl-9Hcarbazole-1,8-disulfonamide

Chemical Property of N₁,N₈-bis(3,5-bis(trifluoromethyl)phenyl)-3,6-di-tert-butyl-9Hcarbazole-1,8-disulfonamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N₁,N₈-bis(3,5-bis(trifluoromethyl)phenyl)-3,6-di-tert-butyl-9Hcarbazole-1,8-disulfonamide

There total 3 articles about N₁,N₈-bis(3,5-bis(trifluoromethyl)phenyl)-3,6-di-tert-butyl-9Hcarbazole-1,8-disulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.0%

3,6-di-tert-butyl-9H-carbazole-1,8-disulfonyl dichloride (1350814-46-8) + 3,5-Bis-(trifluoromethyl)aniline (328-74-5) → N1,N8-bis(3,5-bis(trifluoromethyl)phenyl)-3,6-di-tert-butyl-9Hcarbazole-1,8-disulfonamide (1350814-44-6)

Guidance literature:

With pyridine; In dichloromethane; at 90 ℃; for 2h;

DOI:10.1039/c1ob06126g

Reference yield:

3,6-di-tert-butyl-9H-carbazole-1,8-disulfonic acid (1350814-45-7) → N1,N8-bis(3,5-bis(trifluoromethyl)phenyl)-3,6-di-tert-butyl-9Hcarbazole-1,8-disulfonamide (1350814-44-6)

Guidance literature:

Multi-step reaction with 2 steps

1: phosphorus pentachloride / dichloromethane / 20 °C

2: pyridine / dichloromethane / 2 h / 90 °C

With pyridine; phosphorus pentachloride; In dichloromethane;

DOI:10.1039/c1ob06126g

Reference yield:

3,6-di(tert-butyl)-9H-carbazole (37500-95-1) → N1,N8-bis(3,5-bis(trifluoromethyl)phenyl)-3,6-di-tert-butyl-9Hcarbazole-1,8-disulfonamide (1350814-44-6)

Guidance literature:

Multi-step reaction with 3 steps

1.1: dichloromethane / 0 °C / Inert atmosphere

1.2: 0.5 h / Inert atmosphere

2.1: phosphorus pentachloride / dichloromethane / 20 °C

3.1: pyridine / dichloromethane / 2 h / 90 °C

With pyridine; phosphorus pentachloride; In dichloromethane;

DOI:10.1039/c1ob06126g

upstream raw materials:

3,6-di-tert-butyl-9H-carbazole-1,8-disulfonic acid

3,6-di-tert-butyl-9H-carbazole-1,8-disulfonyl dichloride

3,5-Bis-(trifluoromethyl)aniline

3,6-di(tert-butyl)-9H-carbazole

Downstream raw materials:

C₁₆H₃₆N⁽¹⁺⁾*C₃₆H₃₁F₁₂N₃O₄S₂*I^(1-)